gene detail

Gene description

TAIR ID: AT4G19710

Short description: aspartate kinase-homoserine dehydrogenase ii

Pathogen responsiveness: -0.95

General responsiveness: -1.65

Orthologous

Rice:

OS08G0342400 OS07G0300900

Maize: No orthologous gene

Wheat: No orthologous gene

GO biological process

threonine biosynthetic process, methionine biosynthetic process, aspartate family amino acid biosynthetic process, lysine biosynthetic process via diaminopimelate, phosphorylation, oxidation-reduction process, homoserine biosynthetic process

GO cellular component

chloroplast, chloroplast stroma

GO molecular function

NADP binding, homoserine dehydrogenase activity, aspartate kinase activity, ATP binding

Protein domain

Pfam	PF00696, Amino acid kinase family
Pfam	PF01842, ACT domain
Pfam	PF13840, ACT domain
Pfam	PF03447, Homoserine dehydrogenase, NAD binding domain
Pfam	PF00742, Homoserine dehydrogenase

Metabolic pathway

PWY-3001: isoleucine biosynthesis I
PWY-724: superpathway of lysine, threonine and methionine biosynthesis II
THRESYN-PWY: threonine biosynthesis
PWY-5097: lysine biosynthesis VI
HOMOSERSYN-PWY: homoserine biosynthesis

KEGG pathway

PATH:ath01230: Biosynthesis of amino acids
PATH:ath00260: Glycine, serine and threonine metabolism
PATH:ath00270: Cysteine and methionine metabolism
PATH:ath00300: Lysine biosynthesis
PATH:ath00261: Monobactam biosynthesis

Transcriptional regulation

Regulator:
AT5G13790, AT2G36270, AT5G11260, AT1G24260, AT1G32640

Target:
none

Protein-protein interaction network

No Interactor

Coexpression network

GSE45212_WT_PSTDC3000_AVRRPT2  view
GSE26679_WT_GC  view
GSE56094_WT_HRPA-  view
GSE13739_WT_GO  view
GSE5686_WT_GO  view
GSE56094_WT_PSTDC3000  view
GSE45212_MED14_PSTDC3000_AVRRPT2  view
GSE26679_EDR1_GC  view

Differentially expressed condition

7 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE17500	Col, WT, control 0 h	Col, WT, PstDC3000 24 h	-1.64	9.57E-05
GSE18978	Col, WT, control 24 h	Col, WT, PsmES4326 24 h	-2.89	1.43E-12
GSE37269	Ei2, WT, control	Ei2, WT, TEV 21 d	-1.51	3.12E-02
GSE45212	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 12 h	-1.90	2.31E-13
GSE45212	Col, med14, PstDC3000 AvrRpt2 0 h	Col, med14, PstDC3000 AvrRpt2 12 h	-1.95	1.91E-13
GSE45212	Col, med14, PstDC3000 AvrRpt2 0 h	Col, med14, PstDC3000 AvrRpt2 8 h	-1.60	2.45E-12
GSE9674	Ws-4, AtMYB30 ox, control	Ws-4, AtMYB30 ox, Xanthomonas strain Xcc147 6 h	-1.52	3.10E-03