gene detail

Gene description

TAIR ID: AT3G54470

Short description: uridine 5'-monophosphate synthase / UMP synthase (PYRE-F) (UMPS)

Pathogen responsiveness: NA

General responsiveness: NA

Orthologous

Rice:

OS01G0951200

Maize:

GRMZM2G367026

Wheat:

TA.8467.1.S1_A_AT

GO biological process

'de novo' UMP biosynthetic process, 'de novo' pyrimidine nucleobase biosynthetic process, cellular response to phosphate starvation, response to cadmium ion, nucleoside metabolic process, pyrimidine ribonucleotide biosynthetic process

GO cellular component

cytosol, cytoplasm

GO molecular function

orotidine-5'-phosphate decarboxylase activity, orotate phosphoribosyltransferase activity

Protein domain

Pfam	PF00156, Phosphoribosyl transferase domain
Pfam	PF00215, Orotidine 5'-phosphate decarboxylase / HUMPS family
SMART	SM00934, OMPdecase

Metabolic pathway

PWY-7211: superpathway of pyrimidine deoxyribonucleotides de novo biosynthesis
PWY0-162: superpathway of pyrimidine ribonucleotides de novo biosynthesis
PWY-5686: UMP biosynthesis

KEGG pathway

PATH:ath00240: Pyrimidine metabolism

Transcriptional regulation

Regulator:
AT5G61850

Target:
none

Protein-protein interaction network

The number of partners (degree) is: 1

click to view PPI network

Coexpression network

GSE45212_WT_PSTDC3000_AVRRPT2  view
GSE56094_WT_HRPA-  view
GSE56094_WT_PSTDC3000  view
GSE45212_MED14_PSTDC3000_AVRRPT2  view

Differentially expressed condition

4 conditions

Series	Control	Treatment	Log₂FC	Adj. P value
GSE45212	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 12 h	-2.11	9.20E-15
GSE45212	Col, WT, PstDC3000 AvrRpt2 0 h	Col, WT, PstDC3000 AvrRpt2 8 h	-1.73	1.79E-13
GSE45214	Col, med16, PstDC3000 AvrRpt2 0 h	Col, med16, PstDC3000 AvrRpt2 4 h	-1.54	1.23E-10
GSE56094	Col, WT, control 13 h	Col, WT, PstDC3000 13 h	-1.56	7.81E-10