HVIDB-PPI detail

Q9Y5V3 (MAGED1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Interaction information
PPI score
DEGs post infections
Tissue specific expression

Human protein: MAGD1_HUMAN

UniProtID: Q9Y5V3

Gene name(s): MAGED1;NRAGE;PP2250;PRO2292

Protein name: Melanoma-associated antigen D1

Gene ID: 9500

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
Q9Y5V3-P27958	biogrid,HPIDB	18985028	two hybrid

Evidence suggesting a protein interaction:

Interolog evidence:	none/insignificant.
DDI evidence:	none/insignificant.
Machine learning evidence:	yes (score 0.454).

Combined Score: 0.958

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE68673	A549_uninfected	A549_infected	down	-1.57	3.92e-11	RNA-Seq data
GSE27702	control_macrophages	FPV-infected_macrophages	down	-2.36	5.65e-03	Microarray data
GSE28166	mock_infected_18h	VN1203_infected_18h	down	-2.09	3.73e-04	Microarray data
GSE28166	mock_infected_24h	VN1203_infected_24h	down	-2.89	3.61e-05	Microarray data
GSE30589	Vero_E6_Mock_infected_15hpi	Vero_E6_SARS-Cov_DeltaE_15hpi	down	-2.46	4.24e-07	Microarray data
GSE30589	Vero_E6_Mock_infected_15hpi	Vero_E6_SARS-Cov_WT_15hpi	down	-2.15	1.31e-06	Microarray data
GSE32140-GPL6480	mock_for_RSV_2h	RSV_infection	down	-2.63	7.94e-06	Microarray data
GSE32155	CRL-5800_unifected	CRL-5807_infected	up	1.53	1.28e-03	Microarray data
GSE32155	CRL-5810_unifected	CRL-1472_infected	down	-2.41	1.79e-05	Microarray data
GSE32155	HTB-3_unifected	HTB-174_infected	up	1.71	6.22e-03	Microarray data
GSE46041	iPS-derived_neurons_uninfected	iPS-derived_neurons_HSV-1-infected	down	-1.52	1.49e-03	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_Anhui01_pCalu3_24h	down	-1.54	4.98e-07	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_NL219_pCalu3_24h	down	-1.93	1.60e-06	Microarray data
GSE59226	Control	Virus_infection	down	-2.75	1.09e-04	Microarray data
GSE97949	uninfected_0h	H7N9_infected_7h	down	-2.18	3.30e-30	RNA-Seq data
GSE65574	MCL001_mock_0h	MCL001_RFP-MERS_0h	down	-3.50	6.89e-03	Microarray data
GSE65574	MCL001_mock_12h	MCL001_d3-5-MERS_12h	down	-2.74	3.68e-04	Microarray data
GSE65574	MCL001_mock_12h	MCL001_d4B-MERS_12h	down	-4.57	1.18e-05	Microarray data
GSE65574	MCL001_mock_12h	MCL001_RFP-MERS_12h	down	-3.72	1.03e-02	Microarray data
GSE65574	MCL001_mock_7h	MCL001_RFP-MERS_7h	down	-3.99	4.33e-03	Microarray data
GSE89008	HTBE_H5N1_MOI0_mock_infected_12h	HTBE_H5N1_MOI5_infected_12h	down	-2.98	2.62e-46	RNA-Seq data
GSE89008	HTBE_H3N2_MOI0_mock_infected_18h	HTBE_H3N2_MOI5_infected_18h	down	-1.51	2.01e-11	RNA-Seq data
GSE89008	HTBE_H5N1_MOI0_mock_infected_18h	HTBE_H5N1_MOI5_infected_18h	down	-4.32	1.45e-48	RNA-Seq data
GSE97672-GPL16791	MDM-418_H3N2_MOI0_12h	MDM-418_H3N2_MOI2_12h	down	-1.66	2.62e-02	RNA-Seq data
GSE97672-GPL16791	MDM-418_H3N2_MOI0_18h	MDM-418_H3N2_MOI2_18h	down	-2.19	2.77e-15	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_12h	MDM-520_H5N1_MOI2_12h	down	-2.22	1.83e-23	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_18h	MDM-520_H5N1_MOI2_18h	down	-2.81	5.45e-36	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_18h	MDM-513_H5N1_MOI2_18h	down	-2.93	9.95e-30	RNA-Seq data
GSE8961	Mock_infection	HMPV_infection_72h	down	-1.78	1.38e-04	Microarray data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Low tissue specificity

Ensembl ID:	ENSG00000179222
Gene description:	MAGE family member D1
Chromosome:	X
Position	51803007-51902357
Protein class:	Cancer-related genes, Predicted intracellular proteins
Evidence:	Evidence at protein level
Subcellular location:	Cytosol