Q9Y5P8 (PPP2R3B)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: P2R3B_HUMAN

UniProtID: Q9Y5P8

Gene name(s): PPP2R3B;PPP2R3L

Protein name: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta

Gene ID: 28227

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q9Y5P8-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.008). Show
Machine learning evidence: yes (score 0.675).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
6180PPP2R1A-PPP2R3B complex20.50 (1/2)25007185CORUMView
634PPP2R1A-PPP2R3B complex40.25 (1/4)NAhu.MAPView
2431PPP2R1A-PPP2R3B complex40.25 (1/4)NAhu.MAPView
2797STRIPAK complex170.06 (1/17)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE28166mock_infected_24hVN1203_infected_24hdown-2.394.13e-03Microarray data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-2.455.26e-06Microarray data

Human tissue specific expression (TPM)

Small intestine: 0.6 Liver: 0.2 Gallbladder: 1.0 Duodenum: 0.6 Rectum: 0.0 Tonsil: 0.1 Stomach: 0.9 Salivary glanda: 0.1 Adipose tissue: 1.1 Lung: 1.1 Lymph node: 1.1 Pancreas: 0.4 Kidney: 0.2 Colon: 0.4 Appendix: 0.5 Smooth musle: 1.1 Breast: 0.2 Parathyroid gland: 1.1 Esophagus: 0.9 Heart muscle: 4.6 Spleen: 1.4 Skeletal muscle: 14.7 Bone marrow: 2.0 Skin: 2.4 Urinary bladder: 0.2 Cervix, uterine: 1.1 Endometrium: 1.8 Ovary: 1.0 Fallopian tube: 0.0 Seminal vesicle: 0.6 Prostate: 1.4 Epididymis: 0.0 Testis: 4.3 Placenta: 1.7 Thyroid gland: 0.4 Cerebral cortex: 3.0 Adrenal gland: 0.7
Expression value is measured by Transcripts Per Million (TPM)
Tissue enhanced:
TissueExpression (TPM)
skeletal muscle 14.7
Ensembl ID:ENSG00000167393
Gene description:Protein phosphatase 2 regulatory subunit B''beta
Chromosome:X
Position333963-386955
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Endoplasmic reticulum