Human protein: P2R3B_HUMAN
UniProtID: Q9Y5P8
Gene name(s): PPP2R3B;PPP2R3L
Protein name: Serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit beta
Gene ID: 28227
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q9Y5P8-P27958 | PHISTO | 23487458 | protein array |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.010). | Show |
| Machine learning evidence: | yes (score 0.097). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 6180 | PPP2R1A-PPP2R3B complex | 2 | 0.50 (1/2) | 25007185 | CORUM | View |
| 634 | PPP2R1A-PPP2R3B complex | 4 | 0.25 (1/4) | NA | hu.MAP | View |
| 2431 | PPP2R1A-PPP2R3B complex | 4 | 0.25 (1/4) | NA | hu.MAP | View |
| 2797 | STRIPAK complex | 17 | 0.06 (1/17) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE28166 | mock_infected_24h | VN1203_infected_24h | down | -2.39 | 4.13e-03 | Microarray data |
| GSE32140-GPL6480 | mock_for_RSV_2h | RSV_infection | down | -2.45 | 5.26e-06 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Tissue enhanced:
| Tissue | Expression (TPM) |
|---|---|
| skeletal muscle | 14.7 |
| Ensembl ID: | ENSG00000167393 |
| Gene description: | Protein phosphatase 2 regulatory subunit B''beta |
| Chromosome: | X |
| Position | 333963-386955 |
| Protein class: | Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Endoplasmic reticulum |