Human protein: CD2AP_HUMAN
UniProtID: Q9Y5K6
Gene name(s): CD2AP
Protein name: CD2-associated protein
Gene ID: 23607
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q9Y5K6-P27958 | biogrid,HPIDB | 25872741 | affinity chromatography technology |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.015). | Show |
| Machine learning evidence: | yes (score 0.064). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 846 | RICH1/AMOT polarity complex, Flag-Rich1 precipitated | 8 | 0.12 (1/8) | 16678097 | CORUM | View |
| 457 | CD2AP-NUDC | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 3197 | RNF10-CD2AP-ERC2-ERC1 | 4 | 0.50 (2/4) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE14816 | TB40E_mock | TB40E_TB | up | 1.66 | 2.29e-03 | Microarray data |
| GSE24238 | Mock_24h | HCMV_24h | up | 2.52 | 1.37e-02 | Microarray data |
| GSE28166 | mock_infected_18h | VN1203_infected_18h | down | -2.16 | 5.49e-04 | Microarray data |
| GSE28166 | mock_infected_24h | VN1203_infected_24h | down | -2.61 | 9.55e-05 | Microarray data |
| GSE99389 | CD4+_mock_infected_1d | EBOV_infected_1d | up | 1.52 | 3.75e-15 | RNA-Seq data |
| GSE66486 | PBMC_uninfected_control | PBMC_healthy_donor_infected_8h | up | 1.69 | 4.97e-04 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000198087 |
| Gene description: | CD2 associated protein |
| Chromosome: | 6 |
| Position | 47477789-47627263 |
| Protein class: | Disease related genes, Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Plasma membrane, Cytosol |