Q9Y3T9 (NOC2L)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: NOC2L_HUMAN

UniProtID: Q9Y3T9

Gene name(s): NOC2L;NIR

Protein name: Nucleolar complex protein 2 homolog

Gene ID: 26155

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q9Y3T9-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.010). Show
Machine learning evidence: yes (score 0.668).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
284NOC2L-MKI67-CENPV-NO66-DHX33-NOP56-URB1-URB280.12 (1/8)NAhu.MAPView
1098NOP2-NOC2L-SDAD130.33 (1/3)NAhu.MAPView
1337Nop56p-associated pre-rRNA complex1480.05 (7/148)NAhu.MAPView
1809NOC2L-DDX18-GNL1-NOL1040.25 (1/4)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE68673A549_uninfectedA549_infecteddown-2.066.38e-08RNA-Seq data
GSE89008HTBE_H5N1_MOI0_mock_infected_12hHTBE_H5N1_MOI5_infected_12hdown-2.511.81e-36RNA-Seq data
GSE89008HTBE_H5N1_MOI0_mock_infected_18hHTBE_H5N1_MOI5_infected_18hdown-3.609.23e-82RNA-Seq data
GSE97672-GPL16791MDM-418_H3N2_MOI0_06hMDM-418_H3N2_MOI2_06hdown-1.704.59e-11RNA-Seq data
GSE97672-GPL16791MDM-418_H3N2_MOI0_12hMDM-418_H3N2_MOI2_12hdown-2.305.68e-05RNA-Seq data
GSE97672-GPL16791MDM-418_H3N2_MOI0_18hMDM-418_H3N2_MOI2_18hdown-2.011.21e-25RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_12hMDM-520_H5N1_MOI2_12hdown-2.516.28e-30RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hdown-2.855.25e-36RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hdown-3.053.04e-51RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_12hMDM-513_H5N1_MOI2_12hdown-2.261.37e-24RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 17.8 Liver: 8.2 Gallbladder: 21.9 Duodenum: 18.3 Rectum: 12.6 Tonsil: 14.6 Stomach: 16.8 Salivary glanda: 10.7 Adipose tissue: 22.3 Lung: 20.5 Lymph node: 26.5 Pancreas: 6.1 Kidney: 12.5 Colon: 16.5 Appendix: 31.6 Smooth musle: 21.8 Breast: 17.2 Parathyroid gland: 33.9 Esophagus: 30.0 Heart muscle: 15.4 Spleen: 24.2 Skeletal muscle: 16.0 Bone marrow: 18.8 Skin: 42.0 Urinary bladder: 20.1 Cervix, uterine: 20.1 Endometrium: 26.0 Ovary: 21.0 Fallopian tube: 30.7 Seminal vesicle: 23.0 Prostate: 27.5 Epididymis: 12.2 Testis: 39.2 Placenta: 22.8 Thyroid gland: 25.5 Cerebral cortex: 30.3 Adrenal gland: 21.0
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000188976
Gene description:NOC2 like nucleolar associated transcriptional repressor
Chromosome:1
Position944204-959309
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoli