Q9Y3E1 (HDGFL3)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: HDGR3_HUMAN

UniProtID: Q9Y3E1

Gene name(s): HDGFL3;HDGF2;HDGFRP3;CGI-142

Protein name: Hepatoma-derived growth factor-related protein 3

Gene ID: 50810

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q9Y3E1-P27958PHISTO23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.052).
Combined Score: 0.028


Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE32155CRL-5800_unifectedCRL-5807_infecteddown-10.172.18e-07Microarray data
GSE32155CRL-5810_unifectedCRL-1472_infecteddown-1.923.96e-05Microarray data
GSE32155CRL-5810_unifectedCRL-5807_infecteddown-11.631.10e-07Microarray data
GSE32155HTB-3_unifectedHTB-174_infecteddown-10.961.19e-07Microarray data
GSE32155HTB-4_unifectedHTB-174_infecteddown-11.223.37e-07Microarray data
GSE49628Bcells_QuiescentBcells_Activationup2.212.67e-05Microarray data
GSE49628Bcells_QuiescentBcells_EBV_transformedup3.093.15e-05Microarray data
GSE65574MCL001_mock_12hMCL001_d3-5-MERS_12hup1.541.29e-03Microarray data
GSE66486PBMC_uninfected_controlPBMC_healthy_donor_infected_8hup1.722.87e-02Microarray data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hdown-1.521.68e-08RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 1.8 Liver: 0.4 Gallbladder: 6.3 Duodenum: 1.2 Rectum: 2.9 Tonsil: 2.0 Stomach: 1.9 Salivary glanda: 0.6 Adipose tissue: 5.0 Lung: 5.3 Lymph node: 3.2 Pancreas: 0.3 Kidney: 3.5 Colon: 2.2 Appendix: 4.0 Smooth musle: 7.7 Breast: 5.0 Parathyroid gland: 33.0 Esophagus: 4.0 Heart muscle: 3.7 Spleen: 4.7 Skeletal muscle: 0.8 Bone marrow: 1.5 Skin: 2.2 Urinary bladder: 4.9 Cervix, uterine: 7.1 Endometrium: 10.1 Ovary: 6.0 Fallopian tube: 6.8 Seminal vesicle: 6.5 Prostate: 8.0 Epididymis: 10.1 Testis: 17.6 Placenta: 4.4 Thyroid gland: 10.8 Cerebral cortex: 19.5 Adrenal gland: 7.6
Expression value is measured by Transcripts Per Million (TPM)
Tissue enhanced:
TissueExpression (TPM)
parathyroid gland 33.0
Ensembl ID:ENSG00000166503
Gene description:Hepatoma-derived growth factor-related protein 3
Chromosome:15
Position83112738-83208018
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm