HVIDB-PPI detail

Homo sapiens

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Human protein: HAOX1_HUMAN

UniProtID: Q9UJM8

Gene name(s): HAO1;GOX1;HAOX1

Protein name: Hydroxyacid oxidase 1

Gene ID: 54363

HDF/HRF: NA

Virus protein: RNA-directed RNA polymerase(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037577

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
Q9UJM8-P27958-PRO_0000037577	HPIDB	14623081	two hybrid

Evidence suggesting a protein interaction:

Combined Score: 1.000

Virally targeted human complex

Complex id	Complex name	Complex size	Target ratio	PudMed ID	Source	Detail
684	DBIRD complex	2	0.50 (1/2)	NA	hu.MAP	View

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE83525	B19_NS1_unexpressed	B19_NS1_expressed	up	4.70	9.18e-12	RNA-Seq data
GSE38941	nomal_liver	HBV-associated_acute_liver_failure_liver	down	-3.84	7.93e-05	Microarray data
GSE45042	ELC001_mock_infected_24h	ECL001_EMC_infected_24h	up	4.24	2.08e-04	Microarray data
GSE89008	HTBE_H5N1_MOI0_mock_infected_12h	HTBE_H5N1_MOI5_infected_12h	up	7.69	4.93e-03	RNA-Seq data
GSE97672-GPL16791	MDM-418_H3N2_MOI0_06h	MDM-418_H3N2_MOI2_06h	up	7.14	4.27e-03	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_12h	MDM-520_H5N1_MOI2_12h	up	7.92	7.10e-04	RNA-Seq data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Tissue	Expression (TPM)
liver	308.6

Ensembl ID:	ENSG00000101323
Gene description:	Hydroxyacid oxidase 1
Chromosome:	20
Position	7882981-7940474
Protein class:	Enzymes, Predicted intracellular proteins
Evidence:	Evidence at protein level
Subcellular location: