Human protein: SRTD1_HUMAN
UniProtID: Q9UHV2
Gene name(s): SERTAD1;SEI1;TRIPBR1
Protein name: SERTA domain-containing protein 1
Gene ID: 29950
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q9UHV2-P27958 | PHISTO | 23487458 | protein array |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.009). | Show |
| Machine learning evidence: | yes (score 0.242). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 5107 | p34(SEI-1)-CDK4-CyclinD2 complex | 3 | 0.33 (1/3) | 15065884 | CORUM | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE101760 | control_infected | PR8_NS1_infected | up | 3.43 | 1.89e-14 | RNA-Seq data |
| GSE101760 | mock_infected | PR8_NS1_infected | up | 3.18 | 6.56e-12 | RNA-Seq data |
| GSE102481 | mock_infected_18h | RVFV_ZH548_infected_18h | up | 1.88 | 4.24e-03 | RNA-Seq data |
| GSE78711-GPL15520 | NPC_mock_infected | NPC_Zika_infected | up | 1.67 | 4.91e-03 | RNA-Seq data |
| GSE28166 | mock_infected_24h | VN1203_infected_24h | up | 2.19 | 1.06e-04 | Microarray data |
| GSE30723 | AMs_control_24h | AMs_PR8_24h | up | 2.08 | 8.85e-04 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-1472_infected | down | -1.69 | 5.96e-05 | Microarray data |
| GSE46041 | iPS-derived_neurons_uninfected | iPS-derived_neurons_HSV-1-infected | up | 2.42 | 2.34e-04 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_Anhui01_pCalu3_24h | up | 3.10 | 2.42e-08 | Microarray data |
| GSE85493 | MeWo_uninfected_36h | MeWo_Y920F_infected_36h | up | 1.72 | 2.41e-03 | RNA-Seq data |
| GSE85493 | MeWo_uninfected_36h | MeWo_Y881-920F_infected_36h | up | 1.53 | 2.09e-02 | RNA-Seq data |
| GSE65574 | MCL001_mock_24h | MCL001_d3-5-MERS_24h | up | 4.14 | 1.14e-04 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_d4B-MERS_24h | up | 2.92 | 1.44e-04 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_RFP-MERS_24h | up | 1.87 | 1.11e-02 | Microarray data |
| GSE65699 | PRE_mock | PRE_infection_RKAA | up | 1.65 | 1.21e-09 | Microarray data |
| GSE87750-GPL16791 | hNCC_mock_infected | hNCC_ZIKV-PRVABC59_infected | up | 1.81 | 9.62e-03 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-315_H1N1_MOI0_18h | MDM-315_H1N1_MOI2_18h | up | 1.62 | 8.71e-18 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-513_H5N1_MOI0_06h | MDM-513_H5N1_MOI2_06h | down | -3.38 | 6.60e-40 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_06h | MDM-520_H5N1_MOI2_06h | down | -3.22 | 6.20e-52 | RNA-Seq data |
| GSE8961 | Mock_infection | HMPV_infection_72h | up | 1.52 | 3.62e-03 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000197019 |
| Gene description: | SERTA domain containing 1 |
| Chromosome: | 19 |
| Position | 40421592-40426025 |
| Protein class: | Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm, Golgi apparatus |