Q9P0L0 (VAPA)

Homo sapiens

P27958-PRO_0000037577 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: VAPA_HUMAN

UniProtID: Q9P0L0

Gene name(s): VAPA;VAP33

Protein name: Vesicle-associated membrane protein-associated protein A

Gene ID: 9218

HDF/HRF: NA

Virus protein: RNA-directed RNA polymerase(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037577

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q9P0L0-P27958-PRO_0000037577HPIDB16227268anti tag coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 1.000). Show
DDI evidence: yes (score 0.009). Show
Machine learning evidence: yes (score 0.775).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
6538SPG33-VAPA complex20.50 (1/2)24668814CORUMView
3999SPG33-VAPB complex21.00 (2/2)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE49840Hu_Mock_pCalu3_24hHu_Anhui01_pCalu3_24hup1.681.42e-07Microarray data

Human tissue specific expression (TPM)

Small intestine: 33.7 Liver: 18.9 Gallbladder: 50.6 Duodenum: 31.3 Rectum: 38.8 Tonsil: 23.9 Stomach: 36.3 Salivary glanda: 13.8 Adipose tissue: 35.6 Lung: 49.0 Lymph node: 29.3 Pancreas: 8.6 Kidney: 34.8 Colon: 38.4 Appendix: 32.8 Smooth musle: 39.9 Breast: 36.7 Parathyroid gland: 41.8 Esophagus: 35.1 Heart muscle: 24.6 Spleen: 36.4 Skeletal muscle: 23.5 Bone marrow: 60.5 Skin: 31.1 Urinary bladder: 35.0 Cervix, uterine: 36.5 Endometrium: 43.4 Ovary: 43.6 Fallopian tube: 42.7 Seminal vesicle: 31.0 Prostate: 39.4 Epididymis: 30.1 Testis: 53.7 Placenta: 42.5 Thyroid gland: 59.0 Cerebral cortex: 55.5 Adrenal gland: 61.3
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000101558
Gene description:VAMP associated protein A
Chromosome:18
Position9914002-9960021
Protein class:Plasma proteins, Predicted membrane proteins
Evidence:Evidence at protein level
Subcellular location:Endoplasmic reticulum