Q9HCS5 (EPB41L4A)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: E41LA_HUMAN

UniProtID: Q9HCS5

Gene name(s): EPB41L4A;EPB41L4

Protein name: Band 4.1-like protein 4A

Gene ID: 64097

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q9HCS5-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.681).
Combined Score: 1.000


Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE84346uninfected_controlHCV_infected_high_ISGup2.184.21e-04RNA-Seq data
GSE84346uninfected_controlHCV_infected_low_ISGup1.637.51e-03RNA-Seq data
GSE84897MKN7_WT_controlMKN7_EBV_infecteddown-8.868.97e-03RNA-Seq data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-2.519.23e-06Microarray data
GSE32155HTB-4_unifectedHTB-174_infecteddown-2.795.78e-04Microarray data
GSE43794NPCs_jCV_infection_0hNPCs_jCV_infection_30dup1.617.41e-07Microarray data
GSE45042ELC001_mock_infected_24hECL001_EMC_infected_24hdown-1.771.42e-03Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_Anhui01_pCalu3_24hdown-2.654.29e-08Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_NL219_pCalu3_24hdown-2.174.61e-07Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_Pan99_pCalu3_24hdown-1.702.97e-06Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_VN1203_pCalu3_24hdown-2.661.36e-07Microarray data
GSE99298mock_infected_0hhRSV_NS1_L132A_L133A_infected_96hdown-3.614.21e-04RNA-Seq data
GSE97672-GPL16791MDM-418_H3N2_MOI0_18hMDM-418_H3N2_MOI2_18hup5.942.61e-08RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_12hMDM-520_H5N1_MOI2_12hup1.535.25e-03RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 3.8 Liver: 1.6 Gallbladder: 21.5 Duodenum: 2.6 Rectum: 5.2 Tonsil: 3.3 Stomach: 5.2 Salivary glanda: 3.1 Adipose tissue: 9.4 Lung: 11.6 Lymph node: 3.9 Pancreas: 1.0 Kidney: 12.4 Colon: 3.9 Appendix: 4.3 Smooth musle: 4.1 Breast: 6.7 Parathyroid gland: 25.6 Esophagus: 11.0 Heart muscle: 5.8 Spleen: 6.5 Skeletal muscle: 1.4 Bone marrow: 2.1 Skin: 10.4 Urinary bladder: 6.4 Cervix, uterine: 6.2 Endometrium: 7.0 Ovary: 7.1 Fallopian tube: 11.9 Seminal vesicle: 7.5 Prostate: 9.2 Epididymis: 15.4 Testis: 11.5 Placenta: 13.4 Thyroid gland: 22.4 Cerebral cortex: 11.7 Adrenal gland: 5.9
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000129595
Gene description:Erythrocyte membrane protein band 4.1 like 4A
Chromosome:5
Position112142441-112419316
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm, Plasma membrane