Human protein: KANL2_HUMAN
UniProtID: Q9H9L4
Gene name(s): KANSL2;C12orf41;NSL2
Protein name: KAT8 regulatory NSL complex subunit 2
Gene ID: 54934
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q9H9L4-P27958 | PHISTO | 23487458 | protein array |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.013). | Show |
| Machine learning evidence: | yes (score 0.109). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 7221 | NSL complex | 9 | 0.22 (2/9) | 20018852 | CORUM | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE13637 | HUVEC_control | FPV-infected_HUVEC | down | -1.82 | 8.45e-04 | Microarray data |
| GSE27702 | control_macrophages | FPV-infected_macrophages | down | -1.81 | 1.06e-02 | Microarray data |
| GSE27702 | control_macrophages | H5N1-infected_macrophages | down | -1.59 | 1.22e-02 | Microarray data |
| GSE28166 | mock_infected_18h | VN1203_infected_18h | up | 2.09 | 6.70e-04 | Microarray data |
| GSE28166 | mock_infected_24h | VN1203_infected_24h | up | 2.98 | 5.63e-05 | Microarray data |
| GSE31524 | H1N1_Mock_infection_10h | H1N1_infection_10h | down | -2.16 | 1.13e-05 | Microarray data |
| GSE45042 | ELC001_mock_infected_24h | ECL001_EMC_infected_24h | up | 1.88 | 1.39e-04 | Microarray data |
| GSE46041 | iPS-derived_neurons_uninfected | iPS-derived_neurons_HSV-1-infected | up | 2.12 | 1.73e-04 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_Anhui01_pCalu3_24h | up | 1.76 | 6.32e-07 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_VN1203_pCalu3_24h | up | 1.64 | 2.24e-06 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_d3-5-MERS_24h | up | 1.65 | 4.58e-04 | Microarray data |
| GSE97672-GPL16791 | MDM-418_H3N2_MOI0_06h | MDM-418_H3N2_MOI2_06h | down | -1.56 | 5.95e-07 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-513_H5N1_MOI0_06h | MDM-513_H5N1_MOI2_06h | down | -2.18 | 6.74e-14 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_06h | MDM-520_H5N1_MOI2_06h | down | -1.93 | 1.75e-13 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000139620 |
| Gene description: | KAT8 regulatory NSL complex subunit 2 |
| Chromosome: | 12 |
| Position | 48653401-48682238 |
| Protein class: | Predicted intracellular proteins, Predicted secreted proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm, Plasma membrane, Cytosol |