Q9H8S9 (MOB1A)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: MOB1A_HUMAN

UniProtID: Q9H8S9

Gene name(s): MOB1A;C2orf6;MOB4B;MOBK1B;MOBKL1B

Protein name: MOB kinase activator 1A

Gene ID: 55233

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q9H8S9-P27958PHISTO,biogrid,HPIDB,VirusMentha18985028,22810585two hybrid,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.907). Show
DDI evidence: yes (score 0.055). Show
Machine learning evidence: yes (score 0.110).
Combined Score: 0.989


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1653PYGL-MOB1B-MOB1A30.67 (2/3)NAhu.MAPView
2251PYGL-HPRT1-MOB1A30.33 (1/3)NAhu.MAPView
2320PYGL-MOB1A20.50 (1/2)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-2.153.23e-06Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-2.256.35e-07Microarray data
GSE59226ControlVirus_infectiondown-1.831.57e-04Microarray data
GSE65123healthy_seronegative_controlHCV_infecteddown-4.324.37e-02Microarray data

Human tissue specific expression (TPM)

Small intestine: 46.3 Liver: 15.8 Gallbladder: 56.7 Duodenum: 42.7 Rectum: 47.2 Tonsil: 85.6 Stomach: 32.1 Salivary glanda: 8.5 Adipose tissue: 42.1 Lung: 58.2 Lymph node: 107.8 Pancreas: 3.4 Kidney: 51.0 Colon: 40.7 Appendix: 86.8 Smooth musle: 59.6 Breast: 39.3 Parathyroid gland: 44.8 Esophagus: 44.9 Heart muscle: 16.5 Spleen: 84.5 Skeletal muscle: 4.6 Bone marrow: 57.0 Skin: 46.4 Urinary bladder: 52.8 Cervix, uterine: 56.2 Endometrium: 58.9 Ovary: 39.5 Fallopian tube: 54.1 Seminal vesicle: 41.4 Prostate: 49.7 Epididymis: 31.2 Testis: 37.2 Placenta: 51.6 Thyroid gland: 56.3 Cerebral cortex: 21.2 Adrenal gland: 32.6
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000114978
Gene description:MOB kinase activator 1A
Chromosome:2
Position74152528-74178898
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleus, Nucleoli, Cytosol