Human protein: HOIL1_HUMAN
UniProtID: Q9BYM8
Gene name(s): RBCK1;C20orf18;RNF54;UBCE7IP3;XAP3;XAP4
Protein name: RanBP-type and C3HC4-type zinc finger-containing protein 1
Gene ID: 10616
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q9BYM8-P27958 | biogrid,HPIDB | 26577923 | affinity chromatography technology |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.087). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 6178 | LUBAC complex | 3 | 1.00 (3/3) | 21455180 | CORUM | View |
| 6344 | TNF-R1-associated signaling complex | 15 | 0.33 (5/15) | 20005846 | CORUM | View |
| 1142 | SMAD7-SMURF2 complex | 9 | 0.33 (3/9) | NA | hu.MAP | View |
| 1247 | SMAD7-SMURF2 complex | 4 | 0.50 (2/4) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE101760 | control_infected | PR8_NS1_infected | up | 1.59 | 6.66e-03 | RNA-Seq data |
| GSE101760 | mock_infected | PR8_NS1_infected | up | 1.74 | 3.54e-04 | RNA-Seq data |
| GSE61141 | non-asthmatic_Vehicle | non-asthmatic_HRV16 | up | 1.59 | 5.86e-04 | RNA-Seq data |
| GSE15810 | hMSCs_mock-transduced | hMSCs_BV-transduced | up | 1.72 | 9.13e-03 | Microarray data |
| GSE24238 | Mock_24h | HCMV_24h | up | 1.74 | 4.87e-03 | Microarray data |
| GSE28166 | mock_infected_24h | VN1203_infected_24h | down | -1.61 | 1.85e-03 | Microarray data |
| GSE32155 | HTB-3_unifected | HTB-174_infected | down | -1.92 | 1.19e-04 | Microarray data |
| GSE32155 | HTB-4_unifected | HTB-174_infected | down | -2.97 | 1.47e-04 | Microarray data |
| GSE93385 | K048_mock_infected | K048_ZIKV_infected | up | 2.10 | 9.52e-26 | RNA-Seq data |
| GSE59226 | Control | Virus_infection | down | -1.70 | 3.86e-04 | Microarray data |
| GSE65574 | MCL001_mock_0h | MCL001_RFP-MERS_0h | down | -1.71 | 8.41e-03 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d3-5-MERS_12h | down | -1.51 | 2.41e-04 | Microarray data |
| GSE99389 | CD4+_mock_infected_1d | EBOV_infected_1d | up | 1.82 | 4.24e-19 | RNA-Seq data |
| GSE65699 | PRE_mock | PRE_infection_RKAA | up | 1.74 | 5.09e-11 | Microarray data |
| GSE66486 | PBMC_uninfected_control | PBMC_healthy_donor_infected_16h | up | 2.12 | 3.05e-04 | Microarray data |
| GSE66486 | PBMC_uninfected_control | PBMC_healthy_donor_infected_8h | up | 1.85 | 6.32e-04 | Microarray data |
| GSE97672-GPL16791 | MDM-418_H3N2_MOI0_06h | MDM-418_H3N2_MOI2_06h | up | 1.70 | 2.75e-11 | RNA-Seq data |
| GSE99858 | PBMC_control | PBMC_RV16_infection | up | 1.64 | 2.57e-11 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000125826 |
| Gene description: | RANBP2-type and C3HC4-type zinc finger containing 1 |
| Chromosome: | 20 |
| Position | 407498-430966 |
| Protein class: | Disease related genes, Enzymes, Plasma proteins, Potential drug targets, Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: |