Q99733 (NAP1L4)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: NP1L4_HUMAN

UniProtID: Q99733

Gene name(s): NAP1L4;NAP2

Protein name: Nucleosome assembly protein 1-like 4

Gene ID: 4676

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q99733-P27958biogrid,HPIDB22810585affinity chromatography technology

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.978). Show
DDI evidence: yes (score 0.045). Show
Machine learning evidence: yes (score 0.138).
Combined Score: 0.993


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2692Nop56p-associated pre-rRNA complex50.40 (2/5)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView
3261NAP1L4-HIST1H1T-UTP15-NAP1L140.50 (2/4)NAhu.MAPView
3692Nop56p-associated pre-rRNA complex60.33 (2/6)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-1.597.71e-05Microarray data
GSE32140-GPL6947mock_for_influenza_2hinfluenza_infection_2hdown-1.681.10e-03Microarray data
GSE65123healthy_seronegative_controlHCV_infecteddown-3.843.92e-02Microarray data

Human tissue specific expression (TPM)

Small intestine: 43.2 Liver: 17.6 Gallbladder: 51.8 Duodenum: 20.3 Rectum: 37.3 Tonsil: 68.7 Stomach: 36.9 Salivary glanda: 18.7 Adipose tissue: 35.7 Lung: 46.8 Lymph node: 74.2 Pancreas: 6.0 Kidney: 49.3 Colon: 36.0 Appendix: 47.1 Smooth musle: 56.0 Breast: 39.1 Parathyroid gland: 148.6 Esophagus: 42.4 Heart muscle: 60.7 Spleen: 41.4 Skeletal muscle: 24.7 Bone marrow: 30.8 Skin: 35.2 Urinary bladder: 54.6 Cervix, uterine: 49.1 Endometrium: 57.6 Ovary: 47.6 Fallopian tube: 44.3 Seminal vesicle: 44.3 Prostate: 47.4 Epididymis: 20.8 Testis: 107.9 Placenta: 53.3 Thyroid gland: 59.2 Cerebral cortex: 72.3 Adrenal gland: 33.1
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000205531
Gene description:Nucleosome assembly protein 1 like 4
Chromosome:11
Position2944431-2992377
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm