Q96EP0 (RNF31)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: RNF31_HUMAN

UniProtID: Q96EP0

Gene name(s): RNF31;ZIBRA

Protein name: E3 ubiquitin-protein ligase RNF31

Gene ID: 55072

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q96EP0-P27958biogrid,HPIDB26577923affinity chromatography technology

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: yes (score 0.003). Show
Machine learning evidence: yes (score 0.132).
Combined Score: 0.112


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
6178LUBAC complex31.00 (3/3)21455180CORUMView
6344TNF-R1-associated signaling complex150.33 (5/15)20005846CORUMView
4562LUBAC complex40.50 (2/4)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE28166mock_infected_12hVN1203_infected_12hdown-1.921.26e-04Microarray data
GSE28166mock_infected_18hVN1203_infected_18hdown-2.873.56e-04Microarray data
GSE28166mock_infected_24hVN1203_infected_24hdown-2.893.47e-04Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_Anhui01_pCalu3_24hdown-1.573.67e-06Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_VN1203_pCalu3_24hdown-1.947.87e-07Microarray data
GSE65574MCL001_mock_0hMCL001_d3-5-MERS_0hdown-1.664.65e-02Microarray data
GSE65574MCL001_mock_12hMCL001_d3-5-MERS_12hdown-1.861.20e-03Microarray data
GSE99298mock_infected_0hhRSV_NS1_Y125A_infected_96hup5.592.65e-07RNA-Seq data
GSE97672-GPL16791MDM-513_H5N1_MOI0_06hMDM-513_H5N1_MOI2_06hdown-1.571.12e-06RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 17.4 Liver: 6.4 Gallbladder: 28.8 Duodenum: 17.1 Rectum: 18.9 Tonsil: 21.2 Stomach: 17.7 Salivary glanda: 11.1 Adipose tissue: 18.4 Lung: 29.1 Lymph node: 31.1 Pancreas: 4.6 Kidney: 13.1 Colon: 15.9 Appendix: 28.8 Smooth musle: 36.0 Breast: 18.9 Parathyroid gland: 38.6 Esophagus: 20.9 Heart muscle: 11.3 Spleen: 42.0 Skeletal muscle: 12.1 Bone marrow: 18.5 Skin: 44.4 Urinary bladder: 24.4 Cervix, uterine: 20.1 Endometrium: 32.6 Ovary: 28.5 Fallopian tube: 34.3 Seminal vesicle: 24.0 Prostate: 23.0 Epididymis: 22.3 Testis: 29.6 Placenta: 24.2 Thyroid gland: 35.4 Cerebral cortex: 24.5 Adrenal gland: 18.4
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000092098
Gene description:Ring finger protein 31
Chromosome:14
Position24146683-24160661
Protein class:Enzymes, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Cytosol