HVIDB-PPI detail

Q96EH5 (RPL39L)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Interaction information
PPI score
DEGs post infections
Tissue specific expression

Human protein: RL39L_HUMAN

UniProtID: Q96EH5

Gene name(s): RPL39L;RPL39L1

Protein name: 60S ribosomal protein L39-like

Gene ID: 116832

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
Q96EH5-P27958	PHISTO	23487458	protein array

Evidence suggesting a protein interaction:

Interolog evidence:	none/insignificant.
DDI evidence:	yes (score 0.011).	Show
Machine learning evidence:	yes (score 0.083).

Combined Score: 0.072

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE102481	mock_infected_18h	RVFV_MP12_infected_18h	down	-1.72	1.91e-05	RNA-Seq data
GSE102481	mock_infected_18h	RVFV_ZH548_infected_18h	down	-1.77	1.33e-04	RNA-Seq data
GSE27702	control_macrophages	FPV-infected_macrophages	up	2.16	7.03e-03	Microarray data
GSE32155	CRL-5800_unifected	CRL-1472_infected	down	-11.17	8.82e-08	Microarray data
GSE32155	CRL-5810_unifected	CRL-1472_infected	down	-11.74	1.52e-07	Microarray data
GSE32155	HTB-3_unifected	HTB-174_infected	up	2.27	3.19e-04	Microarray data
GSE32155	HTB-4_unifected	HTB-174_infected	up	4.04	6.15e-05	Microarray data
GSE46041	iPS-derived_neurons_uninfected	iPS-derived_neurons_HSV-1-infected	down	-3.77	1.32e-03	Microarray data
GSE49628	Bcells_Quiescent	Bcells_Activation	up	2.98	2.77e-04	Microarray data
GSE49628	Bcells_Quiescent	Bcells_EBV_transformed	up	2.55	8.37e-04	Microarray data
GSE92496	control_vector	HPV16_E6-E7_vector	up	2.03	1.13e-06	RNA-Seq data
GSE65574	MCL001_mock_0h	MCL001_RFP-MERS_0h	down	-3.90	6.61e-03	Microarray data
GSE65574	MCL001_mock_12h	MCL001_d3-5-MERS_12h	down	-1.72	6.00e-04	Microarray data
GSE65574	MCL001_mock_12h	MCL001_d4B-MERS_12h	down	-3.78	1.02e-05	Microarray data
GSE65574	MCL001_mock_12h	MCL001_RFP-MERS_12h	down	-3.02	3.37e-03	Microarray data
GSE65574	MCL001_mock_24h	MCL001_d3-5-MERS_24h	down	-1.95	2.10e-03	Microarray data
GSE65574	MCL001_mock_24h	MCL001_d4B-MERS_24h	down	-1.66	3.63e-03	Microarray data
GSE65574	MCL001_mock_24h	MCL001_RFP-MERS_24h	down	-1.53	2.74e-02	Microarray data
GSE65574	MCL001_mock_7h	MCL001_RFP-MERS_7h	down	-3.56	8.08e-04	Microarray data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_12h	MDM-520_H5N1_MOI2_12h	down	-2.03	1.93e-02	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_12h	MDM-513_H5N1_MOI2_12h	down	-6.65	3.50e-03	RNA-Seq data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Tissue enriched:

Tissue	Expression (TPM)
testis	220.3

Ensembl ID:	ENSG00000163923
Gene description:	Ribosomal protein L39 like
Chromosome:	3
Position	187120948-187180908
Protein class:	Predicted intracellular proteins, Ribosomal proteins
Evidence:	Evidence at protein level
Subcellular location: