Q96DX7 (TRIM44)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: TRI44_HUMAN

UniProtID: Q96DX7

Gene name(s): TRIM44;DIPB

Protein name: Tripartite motif-containing protein 44

Gene ID: 54765

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q96DX7-P27958PHISTO23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.086).
Combined Score: 0.049


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
654TRIM10-TRIM44-TRIM35-FAM193B40.25 (1/4)NAhu.MAPView
3346MTMR1-TRIM10-TRIM44-TRIM3540.25 (1/4)NAhu.MAPView
3505TRIM10-TRIM44-TRIM35-KLHL4140.25 (1/4)NAhu.MAPView
4034TRIM10-FAM193B-TRIM44-KLHL41-TRIM3550.20 (1/5)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE28166mock_infected_24hVN1203_infected_24hdown-2.262.04e-03Microarray data
GSE32155CRL-5800_unifectedCRL-1472_infectedup1.545.70e-05Microarray data
GSE32155CRL-5810_unifectedCRL-1472_infectedup1.523.17e-04Microarray data
GSE65574MCL001_mock_12hMCL001_d3-5-MERS_12hup2.637.58e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hup2.804.34e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d4B-MERS_24hup2.012.48e-02Microarray data
GSE65574MCL001_mock_24hMCL001_RFP-MERS_24hup2.561.83e-02Microarray data
GSE89008HTBE_H5N1_MOI0_mock_infected_18hHTBE_H5N1_MOI5_infected_18hdown-1.545.24e-12RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 13.2 Liver: 7.5 Gallbladder: 18.4 Duodenum: 10.7 Rectum: 12.3 Tonsil: 12.1 Stomach: 10.6 Salivary glanda: 3.9 Adipose tissue: 14.3 Lung: 17.7 Lymph node: 15.0 Pancreas: 3.2 Kidney: 19.2 Colon: 9.8 Appendix: 16.5 Smooth musle: 18.0 Breast: 13.7 Parathyroid gland: 22.8 Esophagus: 10.1 Heart muscle: 7.7 Spleen: 19.4 Skeletal muscle: 3.4 Bone marrow: 3.8 Skin: 9.1 Urinary bladder: 12.0 Cervix, uterine: 16.8 Endometrium: 18.0 Ovary: 12.8 Fallopian tube: 18.2 Seminal vesicle: 15.9 Prostate: 17.0 Epididymis: 12.5 Testis: 12.7 Placenta: 19.1 Thyroid gland: 25.1 Cerebral cortex: 30.7 Adrenal gland: 14.1
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000166326
Gene description:Tripartite motif containing 44
Chromosome:11
Position35662805-35818007
Protein class:Disease related genes, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Vesicles, Plasma membrane