Q8WTV0 (SCARB1)
Homo sapiensP27958-PRO_0000037570 (NA)
Hepatitis C virus genotype 1a (isolate H) (HCV)Human protein: SCRB1_HUMAN
UniProtID: Q8WTV0
Gene name(s): SCARB1;CD36L1;CLA1
Protein name: Scavenger receptor class B member 1
Gene ID: 949
HDF/HRF: NA
Virus protein: Envelope glycoprotein E2(POLG_HCVH) (HCV-H)
UniProtID: P27958-PRO_0000037570
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q8WTV0-P27958-PRO_0000037570 | HPIDB | 12356718 | cross-linking study |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 1576 | DCBLD2-CNTNAP3-SCARB1 | 3 | 0.33 (1/3) | NA | hu.MAP | View |
| 2653 | ITGA8-PLXNA3-PLXNA1-PTPRU-CACNA2D2-FAM234B-CNTNAP3-GALNT13-MBTPS1-SCARB1-DCBLD2-CHST10 | 12 | 0.08 (1/12) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE30723 | AMs_control_24h | AMs_PR8_24h | down | -1.55 | 1.21e-02 | Microarray data |
| GSE32155 | HTB-3_unifected | HTB-174_infected | down | -2.56 | 1.25e-05 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_Anhui01_pCalu3_24h | down | -2.02 | 3.45e-07 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_d3-5-MERS_24h | down | -2.86 | 3.45e-04 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_d4B-MERS_24h | down | -2.40 | 2.45e-03 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_RFP-MERS_24h | down | -1.54 | 1.44e-02 | Microarray data |
| GSE99389 | CD4+_mock_infected_1d | LPS_infected_1d | down | -2.96 | 2.25e-04 | RNA-Seq data |
| GSE980 | monocyte-derived_dendritic_cells_control | MV-infected_dendritic_cells_12h | down | -1.65 | 1.82e-02 | Microarray data |
| GSE980 | monocyte-derived_dendritic_cells_control | MV-infected_dendritic_cells_24h | down | -1.62 | 8.47e-03 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Group enriched:
| Tissue | Expression (TPM) |
|---|---|
| adrenal gland | 758.4 |
| placenta | 287.5 |
| Ensembl ID: | ENSG00000073060 |
| Gene description: | Scavenger receptor class B member 1 |
| Chromosome: | 12 |
| Position | 124776856-124882668 |
| Protein class: | Predicted intracellular proteins, Predicted membrane proteins, Transporters |
| Evidence: | Evidence at protein level |
| Subcellular location: | Vesicles |