HVIDB-PPI detail

Homo sapiens

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Human protein: CLIP4_HUMAN

UniProtID: Q8N3C7

Gene name(s): CLIP4;RSNL2

Protein name: CAP-Gly domain-containing linker protein 4

Gene ID: 79745

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
Q8N3C7-P27958-PRO_0000037566	HPIDB	23487458	protein array

Evidence suggesting a protein interaction:

Combined Score: 0.188

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE64677	mock_infected_72h	WT_infected_72h	up	1.51	8.41e-05	RNA-Seq data
GSE28166	mock_infected_18h	VN1203_infected_18h	down	-1.53	1.73e-03	Microarray data
GSE28166	mock_infected_24h	VN1203_infected_24h	down	-2.55	8.43e-05	Microarray data
GSE30723	AMs_control_24h	AMs_PR8_24h	down	-2.55	3.61e-03	Microarray data
GSE32155	CRL-5800_unifected	CRL-1472_infected	up	2.82	2.90e-04	Microarray data
GSE32155	CRL-5800_unifected	CRL-5807_infected	up	2.89	5.06e-04	Microarray data
GSE32155	HTB-4_unifected	HTB-174_infected	up	1.51	7.65e-03	Microarray data
GSE49628	Bcells_Quiescent	Bcells_EBV_transformed	up	1.84	1.13e-02	Microarray data
GSE50938	extracted_total_RNA_mock-infected_NHDFs	extracted_total_RNA_HCMV-infected_HNDFs_48h_post-infection	down	-1.50	1.05e-04	Microarray data
GSE97672-GPL16791	MDM-315_H1N1_MOI0_12h	MDM-315_H1N1_MOI2_12h	down	-1.66	1.53e-23	RNA-Seq data
GSE97672-GPL16791	MDM-315_H1N1_MOI0_18h	MDM-315_H1N1_MOI2_18h	down	-1.69	1.42e-16	RNA-Seq data
GSE97672-GPL16791	MDM-418_H3N2_MOI0_18h	MDM-418_H3N2_MOI2_18h	down	-2.13	8.14e-37	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_12h	MDM-520_H5N1_MOI2_12h	down	-1.77	4.01e-23	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_18h	MDM-520_H5N1_MOI2_18h	down	-2.54	3.16e-39	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_18h	MDM-513_H5N1_MOI2_18h	down	-1.86	6.06e-36	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_12h	MDM-513_H5N1_MOI2_12h	down	-1.51	1.60e-10	RNA-Seq data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Ensembl ID:	ENSG00000115295
Gene description:	CAP-Gly domain containing linker protein family member 4
Chromosome:	2
Position	29097705-29189643
Protein class:	Predicted intracellular proteins
Evidence:	Evidence at protein level
Subcellular location:	Vesicles