Human protein: LTBP4_HUMAN
UniProtID: Q8N2S1
Gene name(s): LTBP4
Protein name: Latent-transforming growth factor beta-binding protein 4
Gene ID: 8425
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q8N2S1-P27958 | biogrid,HPIDB | 18985028 | two hybrid |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.022). | Show |
| Machine learning evidence: | yes (score 0.260). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 2866 | NLRP3-LTBP4-NLRP5 | 3 | 0.33 (1/3) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE32155 | CRL-5800_unifected | CRL-1472_infected | down | -3.08 | 8.03e-06 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-1472_infected | down | -1.70 | 1.08e-04 | Microarray data |
| GSE32155 | HTB-3_unifected | HTB-174_infected | up | 1.98 | 3.62e-04 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_NL219_pCalu3_24h | up | 1.87 | 6.18e-06 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_VN1203_pCalu3_24h | up | 1.72 | 8.01e-06 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000090006 |
| Gene description: | Latent transforming growth factor beta binding protein 4 |
| Chromosome: | 19 |
| Position | 40592883-40629818 |
| Protein class: | Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: |