Q8IXJ9 (ASXL1)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: ASXL1_HUMAN

UniProtID: Q8IXJ9

Gene name(s): ASXL1;KIAA0978

Protein name: Polycomb group protein ASXL1

Gene ID: 171023

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q8IXJ9-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.026). Show
Machine learning evidence: yes (score 0.764).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
7354ASXL1-HCFC1-OGT complex30.33 (1/3)29556021CORUMView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE46041iPS-derived_neurons_uninfectediPS-derived_neurons_HSV-1-infectedup1.642.42e-04Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_NL219_pCalu3_24hup2.311.35e-06Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_VN1203_pCalu3_24hup1.831.69e-06Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-1.751.73e-04Microarray data

Human tissue specific expression (TPM)

Small intestine: 21.5 Liver: 10.1 Gallbladder: 27.2 Duodenum: 17.9 Rectum: 18.3 Tonsil: 28.3 Stomach: 17.4 Salivary glanda: 5.7 Adipose tissue: 24.1 Lung: 33.3 Lymph node: 38.2 Pancreas: 4.8 Kidney: 17.8 Colon: 15.7 Appendix: 33.9 Smooth musle: 32.7 Breast: 20.9 Parathyroid gland: 34.0 Esophagus: 12.3 Heart muscle: 8.3 Spleen: 34.6 Skeletal muscle: 8.2 Bone marrow: 37.0 Skin: 19.6 Urinary bladder: 17.0 Cervix, uterine: 20.4 Endometrium: 34.4 Ovary: 28.6 Fallopian tube: 29.1 Seminal vesicle: 20.9 Prostate: 23.4 Epididymis: 30.7 Testis: 68.5 Placenta: 31.1 Thyroid gland: 28.1 Cerebral cortex: 24.6 Adrenal gland: 22.4
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000171456
Gene description:Additional sex combs like 1, transcriptional regulator
Chromosome:20
Position32358344-32439319
Protein class:Cancer-related genes, Disease related genes, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleus, Nucleoli