Q8IWP9 (CCDC28A)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: CC28A_HUMAN

UniProtID: Q8IWP9

Gene name(s): CCDC28A;C6orf80

Protein name: Coiled-coil domain-containing protein 28A

Gene ID: 25901

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q8IWP9-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.020). Show
Machine learning evidence: yes (score 0.689).
Combined Score: 1.000


Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE102481mock_infected_18hRVFV_MP12_infected_18hdown-1.863.25e-04RNA-Seq data
GSE102481mock_infected_18hRVFV_ZH548_infected_18hdown-1.741.54e-04RNA-Seq data
GSE27702control_macrophagesFPV-infected_macrophagesup1.946.53e-03Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-1.831.09e-04Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-1.703.71e-05Microarray data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-3.531.78e-07Microarray data
GSE32140-GPL6947mock_for_influenza_2hinfluenza_infection_2hdown-3.091.66e-04Microarray data
GSE59226ControlVirus_infectiondown-2.261.98e-03Microarray data
GSE65123healthy_seronegative_controlHCV_infecteddown-4.443.17e-02Microarray data
GSE65123healthy_seronegative_controlHCV_resolving_infecteddown-5.594.89e-02Microarray data
GSE65574MCL001_mock_24hMCL001_RFP-MERS_24hdown-1.897.50e-03Microarray data
GSE99298mock_infected_0hhRSV_NS1_L132A_L133A_infected_96hdown-6.337.11e-12RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 34.2 Liver: 34.4 Gallbladder: 37.1 Duodenum: 30.7 Rectum: 26.8 Tonsil: 30.7 Stomach: 25.8 Salivary glanda: 22.0 Adipose tissue: 21.5 Lung: 39.0 Lymph node: 39.8 Pancreas: 7.4 Kidney: 62.0 Colon: 23.7 Appendix: 26.3 Smooth musle: 23.5 Breast: 35.4 Parathyroid gland: 63.2 Esophagus: 16.7 Heart muscle: 10.1 Spleen: 40.9 Skeletal muscle: 5.4 Bone marrow: 25.0 Skin: 13.3 Urinary bladder: 37.4 Cervix, uterine: 35.5 Endometrium: 27.4 Ovary: 26.7 Fallopian tube: 57.6 Seminal vesicle: 28.2 Prostate: 40.5 Epididymis: 46.4 Testis: 43.2 Placenta: 45.6 Thyroid gland: 90.7 Cerebral cortex: 35.9 Adrenal gland: 63.2
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000024862
Gene description:Coiled-coil domain containing 28A
Chromosome:6
Position138773509-138793319
Protein class:Disease related genes, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Cytosol