Q86WV6 (STING1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: STING_HUMAN

UniProtID: Q86WV6

Gene name(s): STING1;ERIS;MITA;TMEM173

Protein name: Stimulator of interferon genes protein

Gene ID: 340061

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q86WV6-P27958PHISTO22911572anti tag coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.085).
Combined Score: 0.048


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
6871AMFR-STING-INSIG1 complex, herpes simplex virus 1 induced30.33 (1/3)25526307CORUMView
7405TMEM173-TBK1 complex21.00 (2/2)29547894CORUMView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE15810hMSCs_mock-transducedhMSCs_BV-transducedup1.684.24e-02Microarray data
GSE28166mock_infected_24hVN1203_infected_24hdown-2.261.07e-04Microarray data
GSE32155CRL-5800_unifectedCRL-5807_infectedup7.401.75e-06Microarray data
GSE32155CRL-5810_unifectedCRL-5807_infectedup8.491.18e-05Microarray data
GSE32155HTB-3_unifectedHTB-174_infectedup2.128.57e-05Microarray data
GSE49628Bcells_QuiescentBcells_Activationup1.555.05e-03Microarray data
GSE65574MCL001_mock_12hMCL001_d4B-MERS_12hup1.955.29e-05Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-1.631.51e-02Microarray data
GSE97672-GPL16791MDM-520_H5N1_MOI0_12hMDM-520_H5N1_MOI2_12hdown-1.552.52e-09RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hdown-1.842.55e-08RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hdown-1.851.64e-16RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 14.9 Liver: 3.3 Gallbladder: 38.9 Duodenum: 12.9 Rectum: 18.5 Tonsil: 38.6 Stomach: 10.6 Salivary glanda: 4.8 Adipose tissue: 34.2 Lung: 70.1 Lymph node: 34.4 Pancreas: 1.5 Kidney: 7.5 Colon: 17.8 Appendix: 48.7 Smooth musle: 45.6 Breast: 11.3 Parathyroid gland: 6.3 Esophagus: 19.0 Heart muscle: 34.5 Spleen: 46.6 Skeletal muscle: 2.0 Bone marrow: 25.8 Skin: 13.8 Urinary bladder: 31.9 Cervix, uterine: 45.4 Endometrium: 32.6 Ovary: 22.1 Fallopian tube: 70.7 Seminal vesicle: 37.2 Prostate: 18.7 Epididymis: 6.4 Testis: 7.9 Placenta: 31.8 Thyroid gland: 12.5 Cerebral cortex: 5.8 Adrenal gland: 16.3
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000184584
Gene description:Transmembrane protein 173
Chromosome:5
Position139475534-139482935
Protein class:Disease related genes, Predicted membrane proteins
Evidence:Evidence at protein level
Subcellular location: