Q7L9L4 (MOB1B)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: MOB1B_HUMAN

UniProtID: Q7L9L4

Gene name(s): MOB1B;MOB4A;MOBKL1A

Protein name: MOB kinase activator 1B

Gene ID: 92597

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q7L9L4-P27958PHISTO,biogrid,HPIDB,VirusMentha22810585affinity chromatography technology,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.907). Show
DDI evidence: yes (score 0.055). Show
Machine learning evidence: yes (score 0.044).
Combined Score: 0.969


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1653PYGL-MOB1B-MOB1A30.67 (2/3)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE32155HTB-3_unifectedHTB-174_infectedup2.111.46e-05Microarray data
GSE32155HTB-4_unifectedHTB-174_infectedup1.867.20e-05Microarray data
GSE59226ControlVirus_infectiondown-2.102.28e-04Microarray data
GSE99298mock_infected_0hhRSV_NS1_Y125A_infected_96hdown-2.043.90e-02RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 6.0 Liver: 3.3 Gallbladder: 11.0 Duodenum: 4.7 Rectum: 6.9 Tonsil: 9.5 Stomach: 7.5 Salivary glanda: 3.6 Adipose tissue: 8.2 Lung: 14.4 Lymph node: 13.3 Pancreas: 1.8 Kidney: 24.2 Colon: 5.7 Appendix: 13.0 Smooth musle: 11.3 Breast: 10.5 Parathyroid gland: 21.6 Esophagus: 8.3 Heart muscle: 5.6 Spleen: 12.0 Skeletal muscle: 1.9 Bone marrow: 18.0 Skin: 10.5 Urinary bladder: 7.5 Cervix, uterine: 11.4 Endometrium: 13.1 Ovary: 9.5 Fallopian tube: 14.4 Seminal vesicle: 7.6 Prostate: 15.4 Epididymis: 6.1 Testis: 11.3 Placenta: 12.6 Thyroid gland: 18.5 Cerebral cortex: 18.2 Adrenal gland: 9.8
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000173542
Gene description:MOB kinase activator 1B
Chromosome:4
Position70902326-71022449
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleus, Nucleoli, Cytosol