Q6ZRS2 (SRCAP)

Homo sapiens

P27958-PRO_0000037576 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: SRCAP_HUMAN

UniProtID: Q6ZRS2

Gene name(s): SRCAP;KIAA0309

Protein name: Helicase SRCAP

Gene ID: 10847

HDF/HRF: NA

Virus protein: Non-structural protein 5A(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037576

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q6ZRS2-P27958-PRO_0000037576HPIDB10702287anti bait coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.773).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1413NCOR1 complex100.10 (1/10)11013263CORUMView
304SRCAP-associated chromatin remodeling complex100.10 (1/10)15647280CORUMView
799DMAP1-associated complex100.10 (1/10)14966270CORUMView
641SRCAP-associated chromatin remodeling complex60.17 (1/6)NAhu.MAPView
1032NuA4/Tip60 HAT complex210.05 (1/21)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE32155CRL-5800_unifectedCRL-1472_infectedup3.084.55e-06Microarray data
GSE32155CRL-5800_unifectedCRL-5807_infectedup1.973.02e-04Microarray data
GSE32155CRL-5810_unifectedCRL-1472_infectedup2.678.29e-06Microarray data
GSE32155CRL-5810_unifectedCRL-5807_infectedup1.578.88e-04Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_VN1203_pCalu3_24hdown-1.543.58e-03Microarray data
GSE65123healthy_seronegative_controlHCV_infecteddown-1.584.38e-02Microarray data
GSE99298mock_infected_0hhRSV_NS1_Y125A_infected_96hdown-2.313.37e-02RNA-Seq data
GSE97672-GPL16791MDM-418_H3N2_MOI0_06hMDM-418_H3N2_MOI2_06hdown-2.055.40e-12RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 19.0 Liver: 3.9 Gallbladder: 18.8 Duodenum: 16.9 Rectum: 13.0 Tonsil: 14.3 Stomach: 17.1 Salivary glanda: 8.3 Adipose tissue: 17.9 Lung: 19.0 Lymph node: 20.9 Pancreas: 4.4 Kidney: 11.7 Colon: 14.1 Appendix: 27.2 Smooth musle: 22.8 Breast: 11.8 Parathyroid gland: 55.6 Esophagus: 15.6 Heart muscle: 8.7 Spleen: 27.7 Skeletal muscle: 9.4 Bone marrow: 20.3 Skin: 20.9 Urinary bladder: 15.4 Cervix, uterine: 20.5 Endometrium: 26.8 Ovary: 22.1 Fallopian tube: 25.8 Seminal vesicle: 20.5 Prostate: 22.0 Epididymis: 8.5 Testis: 40.5 Placenta: 19.5 Thyroid gland: 24.2 Cerebral cortex: 23.5 Adrenal gland: 16.9
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000080603
Gene description:Snf2 related CREBBP activator protein
Chromosome:16
Position30698209-30741409
Protein class:Disease related genes, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm, Nuclear bodies