Human protein: TXD11_HUMAN
UniProtID: Q6PKC3
Gene name(s): TXNDC11;EFP1
Protein name: Thioredoxin domain-containing protein 11
Gene ID: 51061
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q6PKC3-P27958 | biogrid,HPIDB | 18985028 | two hybrid |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.010). | Show |
| Machine learning evidence: | yes (score 0.153). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 2041 | EDEM2-TXNDC11 | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 4282 | EDEM2-TXNDC11-FBLN7-ASPH | 4 | 0.25 (1/4) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE32155 | CRL-5800_unifected | CRL-1472_infected | up | 3.01 | 2.21e-06 | Microarray data |
| GSE32155 | CRL-5810_unifected | CRL-1472_infected | up | 2.14 | 3.11e-05 | Microarray data |
| GSE65574 | MCL001_mock_0h | MCL001_d3-5-MERS_0h | down | -1.82 | 3.19e-02 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d3-5-MERS_12h | down | -1.60 | 7.52e-04 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000153066 |
| Gene description: | Thioredoxin domain containing 11 |
| Chromosome: | 16 |
| Position | 11679080-11742878 |
| Protein class: | Predicted intracellular proteins, Predicted membrane proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Plasma membrane, Cytosol |