HVIDB-PPI detail

Homo sapiens

Hepatitis C virus genotype 1a (isolate H) (HCV)

Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: KDM4D_HUMAN

UniProtID: Q6B0I6

Gene name(s): KDM4D;JHDM3D;JMJD2D

Protein name: Lysine-specific demethylase 4D

Gene ID: 55693

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
Q6B0I6-P27958-PRO_0000037566	HPIDB	23487458	protein array

Evidence suggesting a protein interaction:

Combined Score: 0.053

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE102481	mock_infected_18h	RVFV_MP12_infected_18h	up	2.13	4.45e-03	RNA-Seq data
GSE102481	mock_infected_18h	RVFV_ZH548_infected_18h	up	1.58	2.21e-02	RNA-Seq data
GSE28166	mock_infected_18h	VN1203_infected_18h	up	2.63	5.85e-04	Microarray data
GSE28166	mock_infected_24h	VN1203_infected_24h	up	2.32	1.58e-04	Microarray data
GSE32140-GPL6480	mock_for_RSV_2h	RSV_infection	down	-2.28	1.97e-05	Microarray data
GSE46041	iPS-derived_neurons_uninfected	iPS-derived_neurons_HSV-1-infected	down	-1.69	2.50e-03	Microarray data
GSE49840	Hu_Mock_pCalu3_12h	Hu_Anhui01_pCalu3_12h	up	1.61	7.31e-06	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_Anhui01_pCalu3_24h	up	1.52	7.50e-06	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_NL219_pCalu3_24h	down	-3.16	3.02e-03	Microarray data
GSE59226	Control	Virus_infection	up	1.59	4.40e-04	Microarray data
GSE97949	uninfected_0h	H7N9_infected_7h	up	5.20	4.93e-07	RNA-Seq data
GSE97672-GPL16791	MDM-315_H1N1_MOI0_06h	MDM-315_H1N1_MOI2_06h	up	2.33	1.01e-02	RNA-Seq data
GSE89008	HTBE_H5N1_MOI0_mock_infected_18h	HTBE_H5N1_MOI5_infected_18h	up	1.80	1.83e-02	RNA-Seq data
GSE97672-GPL16791	MDM-513_H5N1_MOI0_06h	MDM-513_H5N1_MOI2_06h	up	3.00	6.18e-03	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_12h	MDM-520_H5N1_MOI2_12h	up	2.46	3.76e-06	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_18h	MDM-520_H5N1_MOI2_18h	up	2.51	6.19e-05	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_18h	MDM-513_H5N1_MOI2_18h	up	2.13	3.72e-03	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_12h	MDM-513_H5N1_MOI2_12h	up	2.99	3.67e-05	RNA-Seq data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Tissue	Expression (TPM)
testis	60.7

Ensembl ID:	ENSG00000186280
Gene description:	Lysine demethylase 4D
Chromosome:	11
Position	94973681-94999518
Protein class:	Predicted intracellular proteins
Evidence:	Evidence at protein level
Subcellular location:	Nucleoplasm