Q15717 (ELAVL1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: ELAV1_HUMAN

UniProtID: Q15717

Gene name(s): ELAVL1;HUR

Protein name: ELAV-like protein 1

Gene ID: 1994

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q15717-P27958PHISTO,biogrid,HPIDB,VirusMentha22810585affinity chromatography technology,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.171).
Combined Score: 0.890


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
6838IGF2BP1 complex90.11 (1/9)19029303CORUMView
3820PTBP1-ELAVL1-ANLN30.33 (1/3)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE65123healthy_seronegative_controlHCV_infecteddown-3.064.53e-02Microarray data
GSE89008HTBE_H5N1_MOI0_mock_infected_18hHTBE_H5N1_MOI5_infected_18hdown-1.767.36e-22RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hdown-1.688.23e-12RNA-Seq data
GSE97672-GPL18573MDM-513_H5N1_MOI0_18hMDM-513_H5N1_MOI2_18hdown-1.624.12e-20RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 28.0 Liver: 15.2 Gallbladder: 35.2 Duodenum: 25.4 Rectum: 30.0 Tonsil: 40.3 Stomach: 23.5 Salivary glanda: 12.8 Adipose tissue: 32.1 Lung: 35.3 Lymph node: 46.7 Pancreas: 6.0 Kidney: 26.3 Colon: 28.0 Appendix: 44.4 Smooth musle: 52.3 Breast: 28.1 Parathyroid gland: 61.9 Esophagus: 33.0 Heart muscle: 22.4 Spleen: 41.5 Skeletal muscle: 11.0 Bone marrow: 17.5 Skin: 25.2 Urinary bladder: 34.8 Cervix, uterine: 45.0 Endometrium: 47.5 Ovary: 39.3 Fallopian tube: 55.7 Seminal vesicle: 41.4 Prostate: 43.8 Epididymis: 31.5 Testis: 81.9 Placenta: 46.9 Thyroid gland: 46.7 Cerebral cortex: 33.5 Adrenal gland: 33.5
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000066044
Gene description:ELAV like RNA binding protein 1
Chromosome:19
Position7958579-8005659
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleus, Nucleoli, Cytosol