Q14919 (DRAP1)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: NC2A_HUMAN

UniProtID: Q14919

Gene name(s): DRAP1

Protein name: Dr1-associated corepressor

Gene ID: 10589

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q14919-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.003). Show
Machine learning evidence: yes (score 0.725).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3064RNA polymerase II complex, chromatin structure modifying160.12 (2/16)9710619CORUMView
2340DRAP1-DR120.50 (1/2)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE75699HNBE_control_0hHNBE_infected_24hup1.951.80e-32RNA-Seq data
GSE24238Mock_24hHCMV_24hup2.094.13e-02Microarray data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectionup1.671.42e-05Microarray data
GSE32140-GPL6947mock_for_influenza_2hinfluenza_infection_2hup1.942.08e-03Microarray data
GSE99389CD4+_mock_infected_1dEBOV_infected_1dup1.905.91e-16RNA-Seq data
GSE67198uninfected_control150HA_u_per_mL_Sev_infectedup1.653.41e-08Microarray data

Human tissue specific expression (TPM)

Small intestine: 47.2 Liver: 22.5 Gallbladder: 43.5 Duodenum: 48.0 Rectum: 20.6 Tonsil: 31.2 Stomach: 37.7 Salivary glanda: 19.4 Adipose tissue: 72.0 Lung: 58.0 Lymph node: 68.1 Pancreas: 13.0 Kidney: 32.9 Colon: 35.5 Appendix: 89.4 Smooth musle: 48.3 Breast: 35.8 Parathyroid gland: 50.8 Esophagus: 39.7 Heart muscle: 43.5 Spleen: 88.8 Skeletal muscle: 52.6 Bone marrow: 48.2 Skin: 58.7 Urinary bladder: 33.0 Cervix, uterine: 43.3 Endometrium: 62.0 Ovary: 43.6 Fallopian tube: 47.5 Seminal vesicle: 57.5 Prostate: 62.5 Epididymis: 28.5 Testis: 140.8 Placenta: 53.2 Thyroid gland: 85.3 Cerebral cortex: 132.7 Adrenal gland: 81.2
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000175550
Gene description:DR1 associated protein 1
Chromosome:11
Position65919257-65921561
Protein class:Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Cytosol