Q13442 (PDAP1)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: HAP28_HUMAN

UniProtID: Q13442

Gene name(s): PDAP1;HASPP28

Protein name: 28 kDa heat- and acid-stable phosphoprotein

Gene ID: 11333

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q13442-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.020). Show
Machine learning evidence: yes (score 0.778).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
401PDAP1-ZPR120.50 (1/2)NAhu.MAPView
2387PDAP1-YTHDF1-ZPR130.33 (1/3)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE45042ELC001_mock_infected_24hECL001_EMC_infected_24hdown-1.952.82e-04Microarray data
GSE93861healthy_blood_controlEbola_infectionup1.667.69e-23Microarray data

Human tissue specific expression (TPM)

Small intestine: 19.1 Liver: 10.0 Gallbladder: 18.7 Duodenum: 18.5 Rectum: 20.3 Tonsil: 20.9 Stomach: 17.6 Salivary glanda: 8.7 Adipose tissue: 27.4 Lung: 24.9 Lymph node: 22.1 Pancreas: 3.9 Kidney: 16.1 Colon: 20.2 Appendix: 31.2 Smooth musle: 31.6 Breast: 23.6 Parathyroid gland: 30.7 Esophagus: 19.3 Heart muscle: 17.2 Spleen: 23.5 Skeletal muscle: 37.3 Bone marrow: 14.6 Skin: 23.0 Urinary bladder: 16.9 Cervix, uterine: 27.6 Endometrium: 28.5 Ovary: 21.9 Fallopian tube: 27.5 Seminal vesicle: 29.9 Prostate: 30.8 Epididymis: 21.5 Testis: 24.8 Placenta: 28.0 Thyroid gland: 26.0 Cerebral cortex: 31.5 Adrenal gland: 24.8
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000106244
Gene description:PDGFA associated protein 1
Chromosome:7
Position99392048-99408829
Protein class:Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Plasma membrane, Cytosol