Human protein: SRSF5_HUMAN
UniProtID: Q13243
Gene name(s): SRSF5;HRS;SFRS5;SRP40
Protein name: Serine/arginine-rich splicing factor 5
Gene ID: 6430
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q13243-P27958 | PHISTO | 23487458 | protein array |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.153). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 2589 | PGC-1-SRp40-SRp55-SRp75 complex | 4 | 0.25 (1/4) | 10983978 | CORUM | View |
| 351 | Spliceosome | 143 | 0.04 (6/143) | 12226669 | CORUM | View |
| 491 | Spliceosome | 46 | 0.07 (3/46) | NA | hu.MAP | View |
| 2802 | Spliceosome | 41 | 0.05 (2/41) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE27702 | control_macrophages | H5N1-infected_macrophages | down | -1.65 | 1.15e-02 | Microarray data |
| GSE35473 | MOI_uninfected | MOI_influenza_A_infected | down | -1.59 | 8.23e-03 | Microarray data |
| GSE59226 | Control | Virus_infection | down | -2.13 | 1.88e-04 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | down | -1.57 | 6.78e-05 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000100650 |
| Gene description: | Serine and arginine rich splicing factor 5 |
| Chromosome: | 14 |
| Position | 69726900-69772005 |
| Protein class: | Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleus, Nucleoli |