Human protein: CACO2_HUMAN
UniProtID: Q13137
Gene name(s): CALCOCO2;NDP52
Protein name: Calcium-binding and coiled-coil domain-containing protein 2
Gene ID: 10241
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q13137-P27958 | biogrid,HPIDB | 18985028 | affinity chromatography technology |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.031). | Show |
| Machine learning evidence: | yes (score 0.355). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 627 | CLCN5-CALCOCO2-LGALS8-SLC36A1 | 4 | 0.25 (1/4) | NA | hu.MAP | View |
| 1957 | SLC36A1-LRRC4B-CLCN5-SPPL2A-LGALS8-ADCY6-CALCOCO2-SLC35A5 | 8 | 0.12 (1/8) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE28166 | mock_infected_18h | VN1203_infected_18h | down | -1.97 | 2.69e-03 | Microarray data |
| GSE28166 | mock_infected_24h | VN1203_infected_24h | down | -3.22 | 8.35e-04 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_d4B-MERS_24h | down | -1.61 | 1.16e-03 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_icMERS_24h | down | -1.84 | 1.75e-02 | Microarray data |
| GSE65574 | MCL001_mock_24h | MCL001_RFP-MERS_24h | down | -1.63 | 9.66e-03 | Microarray data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000136436 |
| Gene description: | Calcium binding and coiled-coil domain 2 |
| Chromosome: | 17 |
| Position | 48830988-48866522 |
| Protein class: | Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Vesicles, Cytosol |