Human protein: IFRD2_HUMAN
UniProtID: Q12894
Gene name(s): IFRD2
Protein name: Interferon-related developmental regulator 2
Gene ID: 7866
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q12894-P27958 | PHISTO | 23487458 | protein array |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.035). | Show |
| Machine learning evidence: | yes (score 0.084). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 848 | IFRD2-BTF3L4 | 2 | 0.50 (1/2) | NA | hu.MAP | View |
| 2146 | Ribosome, cytoplasmic | 143 | 0.13 (18/143) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE102481 | mock_infected_18h | RVFV_MP12_infected_18h | down | -1.81 | 4.52e-02 | RNA-Seq data |
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_WT_15hpi | down | -1.72 | 6.30e-06 | Microarray data |
| GSE48121 | PANC-1_cells_control | PANC-1_cells_GLV-1h153_infection_6h | down | -1.61 | 5.93e-07 | Microarray data |
| GSE59226 | Control | Virus_infection | down | -1.50 | 2.23e-04 | Microarray data |
| GSE99298 | mock_infected_0h | hRSV_NS1_Y125A_infected_96h | up | 9.71 | 6.88e-07 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000214706 |
| Gene description: | Interferon related developmental regulator 2 |
| Chromosome: | 3 |
| Position | 50287732-50292918 |
| Protein class: | Predicted intracellular proteins, Predicted membrane proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm |