Q12805 (EFEMP1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: FBLN3_HUMAN

UniProtID: Q12805

Gene name(s): EFEMP1;FBLN3;FBNL

Protein name: EGF-containing fibulin-like extracellular matrix protein 1

Gene ID: 2202

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q12805-P27958biogrid,HPIDB18985028affinity chromatography technology

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: yes (score 0.005). Show
Machine learning evidence: yes (score 0.329).
Combined Score: 0.783


Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE102481mock_infected_18hRVFV_MP12_infected_18hdown-3.911.35e-02RNA-Seq data
GSE102481mock_infected_18hRVFV_ZH548_infected_18hdown-2.213.79e-02RNA-Seq data
GSE84346uninfected_controlHCV_infected_low_ISGup1.791.20e-02RNA-Seq data
GSE19345Mock_infectedHCMV_infected_24hdown-2.464.91e-05Microarray data
GSE28166mock_infected_18hVN1203_infected_18hdown-2.054.92e-04Microarray data
GSE28166mock_infected_24hVN1203_infected_24hdown-2.357.72e-05Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-1.501.83e-05Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-1.571.24e-05Microarray data
GSE46041iPS-derived_neurons_uninfectediPS-derived_neurons_HSV-1-infecteddown-2.021.86e-02Microarray data
GSE49628Bcells_QuiescentBcells_Activationup1.918.89e-05Microarray data
GSE49840Hu_Mock_pCalu3_24hHu_Anhui01_pCalu3_24hdown-3.307.43e-06Microarray data
GSE50938extracted_total_RNA_mock-infected_NHDFsextracted_total_RNA_HCMV-infected_HNDFs_48h_post-infectiondown-3.294.17e-06Microarray data
GSE50938polysomal_RNA_mock-infected_NHDFspolysomal_RNA_HCMV-infected_HNDFs_48h_post-infectiondown-2.309.10e-04Microarray data
GSE93385K048_mock_infectedK048_ZIKV_infectedup3.572.84e-02RNA-Seq data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-3.581.98e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d4B-MERS_24hdown-2.911.30e-03Microarray data
GSE65574MCL001_mock_24hMCL001_RFP-MERS_24hdown-2.278.69e-03Microarray data
GSE89008HTBE_H5N1_MOI0_mock_infected_12hHTBE_H5N1_MOI5_infected_12hdown-1.917.36e-21RNA-Seq data
GSE89008HTBE_H5N1_MOI0_mock_infected_18hHTBE_H5N1_MOI5_infected_18hdown-2.801.12e-71RNA-Seq data
GSE97672-GPL16791MDM-513_H5N1_MOI0_06hMDM-513_H5N1_MOI2_06hdown-6.143.41e-02RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_12hMDM-520_H5N1_MOI2_12hup6.961.53e-02RNA-Seq data
GSE97672-GPL16791MDM-520_H5N1_MOI0_18hMDM-520_H5N1_MOI2_18hup3.162.54e-03RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 43.4 Liver: 5.6 Gallbladder: 230.4 Duodenum: 25.2 Rectum: 97.9 Tonsil: 19.4 Stomach: 31.8 Salivary glanda: 20.3 Adipose tissue: 294.9 Lung: 231.4 Lymph node: 27.7 Pancreas: 6.2 Kidney: 55.1 Colon: 65.6 Appendix: 80.1 Smooth musle: 143.1 Breast: 128.8 Parathyroid gland: 20.0 Esophagus: 58.1 Heart muscle: 56.9 Spleen: 58.8 Skeletal muscle: 2.7 Bone marrow: 0.1 Skin: 66.1 Urinary bladder: 160.0 Cervix, uterine: 48.7 Endometrium: 115.4 Ovary: 232.2 Fallopian tube: 239.3 Seminal vesicle: 209.7 Prostate: 93.3 Epididymis: 139.1 Testis: 15.7 Placenta: 488.7 Thyroid gland: 180.3 Cerebral cortex: 80.0 Adrenal gland: 68.4
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000115380
Gene description:EGF containing fibulin like extracellular matrix protein 1
Chromosome:2
Position55865967-55924139
Protein class:Disease related genes, Plasma proteins, Predicted intracellular proteins, Predicted secreted proteins
Evidence:Evidence at protein level
Subcellular location:Mitochondria