Q07021 (C1QBP)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: C1QBP_HUMAN

UniProtID: Q07021

Gene name(s): C1QBP;GC1QBP;HABP1;SF2P32

Protein name: Complement component 1 Q subcomponent-binding protein

Gene ID: 708

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q07021-P27958-PRO_0000037566HPIDB,UniProt11086025pull down

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.631). Show
DDI evidence: yes (score 0.006). Show
Machine learning evidence: yes (score 0.649).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
1231FIB-associated protein complex60.17 (1/6)14583623CORUMView
4498p32-CBF-DNA complex40.25 (1/4)15243141CORUMView
5611Emerin complex 24150.07 (1/15)17620012CORUMView
5615Emerin complex 52230.13 (3/23)17620012CORUMView
6985ProTalpha C5 complex50.60 (3/5)29106904CORUMView
7298ACTB-ANP32A-C1QBP-PSMA1-PTMA-PSMA1 complex60.50 (3/6)29106904CORUMView
2055ZNF579-RBM23-C1QBP-LBR40.25 (1/4)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-2.938.47e-07Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-3.509.69e-07Microarray data
GSE49628Bcells_QuiescentBcells_EBV_transformedup1.684.14e-03Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-1.748.36e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d4B-MERS_24hdown-1.992.09e-04Microarray data
GSE99298mock_infected_0hhRSV_NS1_1_118_infected_96hup1.831.27e-03RNA-Seq data
GSE99298mock_infected_0hhRSV_NS1_L132A_L133A_infected_96hup1.784.73e-03RNA-Seq data
GSE89008HTBE_H5N1_MOI0_mock_infected_18hHTBE_H5N1_MOI5_infected_18hdown-1.596.32e-16RNA-Seq data
GSE97672-GPL16791MDM-418_H3N2_MOI0_18hMDM-418_H3N2_MOI2_18hdown-1.901.90e-23RNA-Seq data
GSE8961Mock_infectionHMPV_infection_72hdown-2.011.36e-04Microarray data

Human tissue specific expression (TPM)

Small intestine: 86.4 Liver: 68.8 Gallbladder: 77.1 Duodenum: 96.8 Rectum: 157.0 Tonsil: 122.8 Stomach: 62.1 Salivary glanda: 27.3 Adipose tissue: 79.1 Lung: 69.3 Lymph node: 133.8 Pancreas: 11.7 Kidney: 141.5 Colon: 138.2 Appendix: 113.1 Smooth musle: 118.3 Breast: 133.3 Parathyroid gland: 139.9 Esophagus: 104.3 Heart muscle: 74.0 Spleen: 81.8 Skeletal muscle: 60.5 Bone marrow: 74.6 Skin: 61.8 Urinary bladder: 85.3 Cervix, uterine: 87.0 Endometrium: 91.5 Ovary: 64.1 Fallopian tube: 119.4 Seminal vesicle: 102.3 Prostate: 103.6 Epididymis: 83.2 Testis: 116.3 Placenta: 109.1 Thyroid gland: 109.0 Cerebral cortex: 112.7 Adrenal gland: 145.4
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000108561
Gene description:Complement C1q binding protein
Chromosome:17
Position5432777-5448830
Protein class:Cancer-related genes, Plasma proteins, Predicted intracellular proteins, Transporters
Evidence:Evidence at protein level
Subcellular location:Plasma membrane, Mitochondria