Human protein: UBE3A_HUMAN
UniProtID: Q05086
Gene name(s): UBE3A;E6AP;EPVE6AP;HPVE6A
Protein name: Ubiquitin-protein ligase E3A
Gene ID: 7337
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| Q05086-P27958 | biogrid,HPIDB | 17108031 | enzymatic study |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.191). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 5209 | Ubiquilin-proteasome complex | 6 | 0.33 (2/6) | 10983987 | CORUM | View |
| 6860 | E6AP-HERC2-MAPK6-NEURL4 complex | 4 | 0.25 (1/4) | 22645313 | CORUM | View |
| 768 | PA700 complex | 27 | 0.07 (2/27) | NA | hu.MAP | View |
| 1639 | PA700 complex | 30 | 0.10 (3/30) | NA | hu.MAP | View |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000114062 |
| Gene description: | Ubiquitin protein ligase E3A |
| Chromosome: | 15 |
| Position | 25333728-25439056 |
| Protein class: | Disease related genes, Enzymes, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm, Cytosol |