Q02878 (RPL6)

Homo sapiens

P27958-PRO_0000037577 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: RL6_HUMAN

UniProtID: Q02878

Gene name(s): RPL6;TXREB1

Protein name: 60S ribosomal protein L6

Gene ID: 6128

HDF/HRF: NA

Virus protein: RNA-directed RNA polymerase(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037577

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q02878-P27958-PRO_0000037577HPIDB17229681anti tag coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.007). Show
Machine learning evidence: yes (score 0.677).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3055Nop56p-associated pre-rRNA complex1040.12 (12/104)12777385CORUMView
306Ribosome, cytoplasmic800.10 (8/80)14681386CORUMView
30860S ribosomal subunit, cytoplasmic470.13 (6/47)14681386CORUMView
5232TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I)170.18 (3/17)14743216CORUMView
5266TNF-alpha/NF-kappa B signaling complex 6140.36 (5/14)14743216CORUMView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-2.363.27e-07Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-2.421.50e-06Microarray data
GSE65574MCL001_mock_0hMCL001_RFP-MERS_0hdown-1.821.93e-02Microarray data
GSE65574MCL001_mock_12hMCL001_d4B-MERS_12hdown-2.664.35e-05Microarray data
GSE65574MCL001_mock_7hMCL001_RFP-MERS_7hdown-2.101.76e-03Microarray data

Human tissue specific expression (TPM)

Small intestine: 797.8 Liver: 487.7 Gallbladder: 1094.3 Duodenum: 762.8 Rectum: 1269.7 Tonsil: 1878.0 Stomach: 762.4 Salivary glanda: 683.7 Adipose tissue: 992.3 Lung: 927.7 Lymph node: 2005.0 Pancreas: 399.4 Kidney: 952.0 Colon: 1125.2 Appendix: 1199.9 Smooth musle: 1416.9 Breast: 2123.3 Parathyroid gland: 1127.5 Esophagus: 1311.3 Heart muscle: 529.0 Spleen: 1321.7 Skeletal muscle: 488.7 Bone marrow: 1390.9 Skin: 1788.1 Urinary bladder: 1361.2 Cervix, uterine: 1501.6 Endometrium: 1929.3 Ovary: 3221.7 Fallopian tube: 1893.2 Seminal vesicle: 1112.9 Prostate: 1310.1 Epididymis: 1782.9 Testis: 494.7 Placenta: 1030.7 Thyroid gland: 1924.5 Cerebral cortex: 686.0 Adrenal gland: 1232.6
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000089009
Gene description:Ribosomal protein L6
Chromosome:12
Position112405190-112418838
Protein class:Predicted intracellular proteins, Ribosomal proteins
Evidence:Evidence at protein level
Subcellular location:Microtubules, Cytokinetic bridge