Q00325 (SLC25A3)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: MPCP_HUMAN

UniProtID: Q00325

Gene name(s): SLC25A3;PHC;OK/SW-cl.48

Protein name: Phosphate carrier protein

Gene ID: 5250

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
Q00325-P27958PHISTO,biogrid,HPIDB,VirusMentha22810585affinity chromatography technology,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.003). Show
Machine learning evidence: yes (score 0.158).
Combined Score: 0.883


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
6985ProTalpha C5 complex50.60 (3/5)29106904CORUMView
7298ACTB-ANP32A-C1QBP-PSMA1-PTMA-PSMA1 complex60.50 (3/6)29106904CORUMView
128F1F0-ATP synthase, mitochondrial70.29 (2/7)NAhu.MAPView
990Nop56p-associated pre-rRNA complex80.25 (2/8)NAhu.MAPView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2362F1F0-ATP synthase, mitochondrial150.07 (1/15)NAhu.MAPView
2499F1F0-ATP synthase, mitochondrial60.33 (2/6)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE97672-GPL16791MDM-418_H3N2_MOI0_18hMDM-418_H3N2_MOI2_18hdown-1.661.06e-26RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 329.5 Liver: 189.7 Gallbladder: 222.7 Duodenum: 387.2 Rectum: 403.2 Tonsil: 298.2 Stomach: 219.7 Salivary glanda: 98.2 Adipose tissue: 291.3 Lung: 261.1 Lymph node: 235.9 Pancreas: 55.8 Kidney: 442.6 Colon: 344.8 Appendix: 247.6 Smooth musle: 392.8 Breast: 310.7 Parathyroid gland: 595.7 Esophagus: 292.8 Heart muscle: 510.5 Spleen: 187.6 Skeletal muscle: 528.1 Bone marrow: 127.7 Skin: 227.8 Urinary bladder: 234.7 Cervix, uterine: 277.6 Endometrium: 312.2 Ovary: 301.0 Fallopian tube: 312.5 Seminal vesicle: 307.5 Prostate: 298.1 Epididymis: 284.3 Testis: 143.4 Placenta: 289.4 Thyroid gland: 333.7 Cerebral cortex: 259.0 Adrenal gland: 407.3
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000075415
Gene description:Solute carrier family 25 member 3
Chromosome:12
Position98593591-98606379
Protein class:Disease related genes, Plasma proteins, Potential drug targets, Predicted intracellular proteins, Predicted membrane proteins, Transporters
Evidence:Evidence at protein level
Subcellular location:Mitochondria