Human protein: RT22_HUMAN
UniProtID: P82650
Gene name(s): MRPS22;C3orf5;RPMS22;GK002
Protein name: 28S ribosomal protein S22
Gene ID: 56945
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P82650-P27958 | biogrid,HPIDB | 26845356 | two hybrid |
| Interolog evidence: | none/insignificant. |
| DDI evidence: | none/insignificant. |
| Machine learning evidence: | yes (score 0.110). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 315 | 28S ribosomal subunit, mitochondrial | 30 | 0.03 (1/30) | 14681386 | CORUM | View |
| 320 | 55S ribosome, mitochondrial | 78 | 0.01 (1/78) | 14681386 | CORUM | View |
| 1337 | Nop56p-associated pre-rRNA complex | 148 | 0.05 (7/148) | NA | hu.MAP | View |
| 4220 | 28S ribosomal subunit, mitochondrial | 29 | 0.03 (1/29) | NA | hu.MAP | View |
| 4504 | 28S ribosomal subunit, mitochondrial | 28 | 0.04 (1/28) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_WT_15hpi | down | -1.56 | 7.15e-06 | Microarray data |
| GSE49840 | Hu_Mock_pCalu3_24h | Hu_VN1203_pCalu3_24h | down | -1.70 | 4.07e-07 | Microarray data |
| GSE59226 | Control | Virus_infection | down | -2.17 | 2.01e-04 | Microarray data |
| GSE65574 | MCL001_mock_12h | MCL001_d4B-MERS_12h | up | 1.51 | 5.30e-04 | Microarray data |
| GSE89008 | HTBE_H5N1_MOI0_mock_infected_12h | HTBE_H5N1_MOI5_infected_12h | down | -1.68 | 7.08e-11 | RNA-Seq data |
| GSE89008 | HTBE_H5N1_MOI0_mock_infected_18h | HTBE_H5N1_MOI5_infected_18h | down | -2.08 | 1.44e-10 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_12h | MDM-520_H5N1_MOI2_12h | down | -1.79 | 1.97e-18 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_18h | MDM-520_H5N1_MOI2_18h | down | -2.70 | 7.50e-19 | RNA-Seq data |
| GSE97672-GPL18573 | MDM-513_H5N1_MOI0_18h | MDM-513_H5N1_MOI2_18h | down | -1.93 | 3.62e-16 | RNA-Seq data |
| GSE97672-GPL18573 | MDM-513_H5N1_MOI0_12h | MDM-513_H5N1_MOI2_12h | down | -1.52 | 2.47e-08 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000175110 |
| Gene description: | Mitochondrial ribosomal protein S22 |
| Chromosome: | 3 |
| Position | 139005806-139357223 |
| Protein class: | Disease related genes, Predicted intracellular proteins, Predicted secreted proteins, Ribosomal proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Mitochondria |