HVIDB-PPI detail

Homo sapiens

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Human protein: PITX1_HUMAN

UniProtID: P78337

Gene name(s): PITX1;BFT;PTX1

Protein name: Pituitary homeobox 1

Gene ID: 5307

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
P78337-P27958	PHISTO	12620797	anti tag coimmunoprecipitation

Evidence suggesting a protein interaction:

Combined Score: 0.023

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE32155	CRL-5800_unifected	CRL-1472_infected	up	2.66	3.63e-03	Microarray data
GSE32155	CRL-5800_unifected	CRL-5807_infected	up	5.18	2.65e-04	Microarray data
GSE32155	CRL-5810_unifected	CRL-1472_infected	up	2.14	7.19e-04	Microarray data
GSE32155	CRL-5810_unifected	CRL-5807_infected	up	4.66	4.92e-05	Microarray data
GSE32155	HTB-3_unifected	HTB-174_infected	down	-4.94	7.59e-06	Microarray data
GSE32155	HTB-4_unifected	HTB-174_infected	down	-2.86	1.34e-05	Microarray data
GSE46041	iPS-derived_neurons_uninfected	iPS-derived_neurons_HSV-1-infected	up	2.55	1.31e-02	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_Anhui01_pCalu3_24h	up	1.98	1.56e-07	Microarray data
GSE92496	control_vector	HPV16_E6-E7_vector	down	-4.38	4.28e-04	RNA-Seq data
GSE65574	MCL001_mock_7h	MCL001_RFP-MERS_7h	up	1.51	8.51e-04	Microarray data
GSE68503	empty_vector_control	tumor-derived_LT339	up	2.42	2.30e-02	Microarray data
GSE68503	empty_vector_control	tumor-derived_LT339+sT	up	2.25	1.04e-02	Microarray data
GSE89008	HTBE_H5N1_MOI0_mock_infected_18h	HTBE_H5N1_MOI5_infected_18h	down	-1.60	4.76e-09	RNA-Seq data
GSE97672-GPL16791	MDM-315_H1N1_MOI0_12h	MDM-315_H1N1_MOI2_12h	up	2.40	6.12e-05	RNA-Seq data
GSE97672-GPL16791	MDM-315_H1N1_MOI0_18h	MDM-315_H1N1_MOI2_18h	up	2.97	3.82e-04	RNA-Seq data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Tissue	Expression (TPM)
esophagus	211.7

Ensembl ID:	ENSG00000069011
Gene description:	Paired like homeodomain 1
Chromosome:	5
Position	135027735-135034813
Protein class:	Disease related genes, Predicted intracellular proteins, Transcription factors
Evidence:	Evidence at protein level
Subcellular location:	Nucleoli