P62888 (RPL30)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: RL30_HUMAN

UniProtID: P62888

Gene name(s): RPL30

Protein name: 60S ribosomal protein L30

Gene ID: 6156

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P62888-P27958PHISTO23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.089).
Combined Score: 0.051


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3055Nop56p-associated pre-rRNA complex1040.12 (12/104)12777385CORUMView
306Ribosome, cytoplasmic800.10 (8/80)14681386CORUMView
30860S ribosomal subunit, cytoplasmic470.13 (6/47)14681386CORUMView
5232TNF-alpha/Nf-kappa B signaling complex (RPL6, RPL30, RPS13, CHUK, DDX3X, NFKB2, NFKBIB, REL, IKBKG, NFKB1, MAP3K8, RELB, GLG1, NFKBIA, RELA, TNIP2, GTF2I)170.18 (3/17)14743216CORUMView
5266TNF-alpha/NF-kappa B signaling complex 6140.36 (5/14)14743216CORUMView
5380TRBP containing complex (DICER, RPL7A, EIF6, MOV10 and subunits of the 60S ribosomal particle)250.12 (3/25)17507929CORUMView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-2.432.80e-07Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-2.509.24e-07Microarray data
GSE65574MCL001_mock_12hMCL001_d4B-MERS_12hdown-2.133.41e-05Microarray data
GSE65574MCL001_mock_12hMCL001_RFP-MERS_12hdown-2.304.41e-03Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-1.821.88e-03Microarray data
GSE65574MCL001_mock_24hMCL001_d4B-MERS_24hdown-1.889.69e-04Microarray data
GSE65574MCL001_mock_24hMCL001_RFP-MERS_24hdown-1.871.07e-02Microarray data
GSE97672-GPL16791MDM-418_H3N2_MOI0_12hMDM-418_H3N2_MOI2_12hup1.537.14e-03RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 1189.5 Liver: 1033.9 Gallbladder: 1701.8 Duodenum: 1050.8 Rectum: 1849.6 Tonsil: 3004.6 Stomach: 1159.9 Salivary glanda: 850.9 Adipose tissue: 1385.7 Lung: 1621.0 Lymph node: 3159.9 Pancreas: 456.0 Kidney: 1128.0 Colon: 1578.8 Appendix: 1652.4 Smooth musle: 2042.8 Breast: 4238.0 Parathyroid gland: 1227.5 Esophagus: 1520.8 Heart muscle: 735.5 Spleen: 2286.6 Skeletal muscle: 758.6 Bone marrow: 2008.4 Skin: 2171.2 Urinary bladder: 1712.8 Cervix, uterine: 2843.9 Endometrium: 2802.6 Ovary: 5911.7 Fallopian tube: 3547.1 Seminal vesicle: 1821.5 Prostate: 1945.4 Epididymis: 2481.5 Testis: 1060.6 Placenta: 1650.6 Thyroid gland: 2410.3 Cerebral cortex: 730.4 Adrenal gland: 1381.6
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000156482
Gene description:Ribosomal protein L30
Chromosome:8
Position98024851-98046469
Protein class:Plasma proteins, Predicted intracellular proteins, Ribosomal proteins
Evidence:Evidence at protein level
Subcellular location:Endoplasmic reticulum, Cytosol