P62750 (RPL23A)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: RL23A_HUMAN

UniProtID: P62750

Gene name(s): RPL23A

Protein name: 60S ribosomal protein L23a

Gene ID: 6147

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P62750-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: yes (score 0.006). Show
Machine learning evidence: yes (score 0.851).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3055Nop56p-associated pre-rRNA complex1040.12 (12/104)12777385CORUMView
306Ribosome, cytoplasmic800.10 (8/80)14681386CORUMView
30860S ribosomal subunit, cytoplasmic470.13 (6/47)14681386CORUMView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-2.166.28e-07Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-2.042.50e-06Microarray data
GSE32155HTB-3_unifectedHTB-174_infectedup2.281.13e-05Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-1.902.25e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d4B-MERS_24hdown-2.051.01e-03Microarray data
GSE65574MCL001_mock_24hMCL001_RFP-MERS_24hdown-1.872.68e-02Microarray data

Human tissue specific expression (TPM)

Small intestine: 642.4 Liver: 341.5 Gallbladder: 813.8 Duodenum: 602.2 Rectum: 882.7 Tonsil: 1353.3 Stomach: 616.2 Salivary glanda: 465.2 Adipose tissue: 547.1 Lung: 804.9 Lymph node: 1569.6 Pancreas: 211.5 Kidney: 515.8 Colon: 801.8 Appendix: 871.5 Smooth musle: 972.4 Breast: 1770.8 Parathyroid gland: 563.7 Esophagus: 724.6 Heart muscle: 416.3 Spleen: 1257.5 Skeletal muscle: 403.0 Bone marrow: 836.8 Skin: 1300.6 Urinary bladder: 874.3 Cervix, uterine: 1422.7 Endometrium: 1269.3 Ovary: 2755.0 Fallopian tube: 1687.5 Seminal vesicle: 880.9 Prostate: 951.9 Epididymis: 857.6 Testis: 434.5 Placenta: 935.7 Thyroid gland: 953.6 Cerebral cortex: 465.7 Adrenal gland: 812.2
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000198242
Gene description:Ribosomal protein L23a
Chromosome:17
Position28719393-28724359
Protein class:Plasma proteins, Predicted intracellular proteins, Ribosomal proteins
Evidence:Evidence at protein level
Subcellular location: