P62314 (SNRPD1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: SMD1_HUMAN

UniProtID: P62314

Gene name(s): SNRPD1

Protein name: Small nuclear ribonucleoprotein Sm D1

Gene ID: 6632

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P62314-P27958PHISTO14524621anti bait coimmunoprecipitation

Evidence suggesting a protein interaction:

Interolog evidence: none/insignificant.
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.147).
Combined Score: 0.122


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
106812S U11 snRNP150.07 (1/15)15146077CORUMView
1142SMN complex100.10 (1/10)10601333CORUMView
1143SMN complex160.06 (1/16)17178713CORUMView
1181C complex spliceosome800.06 (5/80)11991638CORUMView
1183CDC5L complex300.03 (1/30)11101529CORUMView
1745SMN complex150.07 (1/15)11748230CORUMView
1746SMN containing complex80.12 (1/8)11522829CORUMView
275517S U2 snRNP330.09 (3/33)12234937CORUMView
3118SMN1-SIP1-SNRP complex70.14 (1/7)9323129CORUMView
351Spliceosome1430.04 (6/143)12226669CORUMView
43018S U11/U12 snRNP240.04 (1/24)15146077CORUMView
5613Emerin complex 25160.12 (2/16)17620012CORUMView
5615Emerin complex 52230.13 (3/23)17620012CORUMView
81920S methylosome-SmD complex40.25 (1/4)11713266CORUMView
8336S methyltransferase complex30.33 (1/3)11713266CORUMView
83420S methylosome and RG-containing Sm protein complex60.17 (1/6)11713266CORUMView
8356S methyltransferase and RG-containing Sm proteins complex80.12 (1/8)11713266CORUMView
822Spliceosome450.02 (1/45)NAhu.MAPView
3233Spliceosome280.04 (1/28)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE48121PANC-1_cells_controlPANC-1_cells_GLV-1h153_infection_6hdown-1.981.56e-07Microarray data
GSE65574MCL001_mock_0hMCL001_d3-5-MERS_0hdown-1.713.64e-02Microarray data
GSE65574MCL001_mock_12hMCL001_d3-5-MERS_12hdown-3.285.49e-04Microarray data
GSE65574MCL001_mock_12hMCL001_d4B-MERS_12hdown-1.671.65e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-1.959.91e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d4B-MERS_24hdown-1.903.24e-03Microarray data
GSE99298mock_infected_0hhRSV_NS1_Y125A_infected_96hdown-1.835.26e-05RNA-Seq data
GSE93861healthy_blood_controlEbola_infectionup2.262.15e-19Microarray data

Human tissue specific expression (TPM)

Small intestine: 48.2 Liver: 15.3 Gallbladder: 34.9 Duodenum: 41.3 Rectum: 48.2 Tonsil: 63.9 Stomach: 33.1 Salivary glanda: 11.4 Adipose tissue: 37.4 Lung: 25.8 Lymph node: 81.2 Pancreas: 4.0 Kidney: 25.7 Colon: 44.9 Appendix: 71.0 Smooth musle: 40.8 Breast: 37.5 Parathyroid gland: 20.5 Esophagus: 42.3 Heart muscle: 11.6 Spleen: 40.7 Skeletal muscle: 15.9 Bone marrow: 55.3 Skin: 23.7 Urinary bladder: 35.5 Cervix, uterine: 26.5 Endometrium: 43.7 Ovary: 38.2 Fallopian tube: 41.9 Seminal vesicle: 24.5 Prostate: 35.4 Epididymis: 31.0 Testis: 63.8 Placenta: 50.7 Thyroid gland: 29.6 Cerebral cortex: 53.0 Adrenal gland: 43.6
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000167088
Gene description:Small nuclear ribonucleoprotein D1 polypeptide
Chromosome:18
Position21612267-21633524
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location: