Human protein: SUMO2_HUMAN
UniProtID: P61956
Gene name(s): SUMO2;SMT3B;SMT3H2
Protein name: Small ubiquitin-related modifier 2
Gene ID: 6613
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P61956-P27958 | PHISTO,biogrid,HPIDB,VirusMentha | 22810585 | affinity chromatography technology,tandem affinity purification |
| Interolog evidence: | yes (score 0.696). | Show |
| DDI evidence: | none/insignificant. | |
| Machine learning evidence: | yes (score 0.207). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 38 | AAAS-TMEM214-GLE1-SMPD4-UBE2I-SUMO2-TMEM209-NDC1-SENP2-RCC1-SUMO1-NXF1-NEMP1 | 13 | 0.08 (1/13) | NA | hu.MAP | View |
| 4642 | RANGAP1-UBE2I-SUMO2-RCC1-NUP50-SENP1-SENP2-DLGAP5-NEMP1 | 9 | 0.11 (1/9) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE100839 | mock_infected | EBOV_infected | up | 1.65 | 1.27e-15 | RNA-Seq data |
| GSE79968 | IMR90_GFP_24h | IMR90_MCPyV_ST_24h | down | -2.30 | 3.64e-03 | RNA-Seq data |
| GSE79968 | IMR90_GFP_40h | IMR90_MCPyV_ST_40h | up | 2.85 | 9.53e-03 | RNA-Seq data |
| GSE79968 | IMR90_GFP_64h | IMR90_MCPyV_ST_64h | down | -3.05 | 3.21e-58 | RNA-Seq data |
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_DeltaE_15hpi | down | -2.72 | 2.37e-07 | Microarray data |
| GSE30589 | Vero_E6_Mock_infected_15hpi | Vero_E6_SARS-Cov_WT_15hpi | down | -2.39 | 1.78e-05 | Microarray data |
| GSE85493 | MeWo_uninfected_36h | MeWo_Y881F_infected_36h | down | -2.67 | 9.58e-15 | RNA-Seq data |
| GSE85493 | MeWo_uninfected_36h | MeWo_pOka-WT_infected_36h | down | -2.88 | 1.15e-13 | RNA-Seq data |
| GSE85493 | MeWo_uninfected_36h | MeWo_Y920F_infected_36h | down | -2.56 | 6.68e-14 | RNA-Seq data |
| GSE85493 | MeWo_uninfected_36h | MeWo_Y881-920F_infected_36h | down | -2.65 | 1.49e-13 | RNA-Seq data |
| GSE93385 | K048_mock_infected | K048_ZIKV_infected | up | 2.17 | 3.87e-03 | RNA-Seq data |
| GSE99298 | mock_infected_0h | hRSV_NS1_Y125A_infected_96h | down | -6.70 | 1.50e-16 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
| Ensembl ID: | ENSG00000188612 |
| Gene description: | Small ubiquitin-like modifier 2 |
| Chromosome: | 17 |
| Position | 75165586-75182983 |
| Protein class: | Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Nucleoplasm, Nuclear bodies |