HVIDB-PPI detail

Homo sapiens

Hepatitis C virus genotype 1a (isolate H) (HCV)

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Human protein: KLF3_HUMAN

UniProtID: P57682

Gene name(s): KLF3;BKLF

Protein name: Krueppel-like factor 3

Gene ID: 51274

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae

Interaction	Source database	PubMed ID	Detection method
P57682-P27958-PRO_0000037566	HPIDB	23487458	protein array

Evidence suggesting a protein interaction:

Combined Score: 0.121

Differentially expression condition

Series	Control	Treatment	Regulation	Log2FC	Adj.P.Val	Data type
GSE13637	HUVEC_control	PR8-infected_IKK2kd-transfected_HUVEC	down	-1.51	1.23e-04	Microarray data
GSE28166	mock_infected_12h	VN1203_infected_12h	down	-2.49	1.75e-04	Microarray data
GSE28166	mock_infected_18h	VN1203_infected_18h	down	-3.29	1.02e-03	Microarray data
GSE28166	mock_infected_24h	VN1203_infected_24h	down	-2.77	4.18e-04	Microarray data
GSE31524	H1N1_Mock_infection_10h	H1N1_infection_10h	down	-1.94	8.61e-06	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_NL219_pCalu3_24h	down	-2.87	5.22e-07	Microarray data
GSE49840	Hu_Mock_pCalu3_24h	Hu_VN1203_pCalu3_24h	down	-3.13	2.70e-07	Microarray data
GSE65574	MCL001_mock_12h	MCL001_d3-5-MERS_12h	up	2.72	1.72e-04	Microarray data
GSE65574	MCL001_mock_12h	MCL001_d4B-MERS_12h	up	1.88	9.87e-05	Microarray data
GSE65574	MCL001_mock_24h	MCL001_d4B-MERS_24h	up	1.72	3.00e-04	Microarray data
GSE89008	HTBE_H5N1_MOI0_mock_infected_6h	HTBE_H5N1_MOI5_infected_6h	down	-2.29	4.39e-15	RNA-Seq data
GSE89008	HTBE_H5N1_MOI0_mock_infected_12h	HTBE_H5N1_MOI5_infected_12h	down	-2.51	8.47e-14	RNA-Seq data
GSE89008	HTBE_H5N1_MOI0_mock_infected_18h	HTBE_H5N1_MOI5_infected_18h	down	-2.68	5.16e-17	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_06h	MDM-520_H5N1_MOI2_06h	down	-1.74	7.83e-06	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_12h	MDM-520_H5N1_MOI2_12h	down	-1.86	1.06e-09	RNA-Seq data
GSE97672-GPL16791	MDM-520_H5N1_MOI0_18h	MDM-520_H5N1_MOI2_18h	down	-1.50	1.73e-05	RNA-Seq data
GSE97672-GPL18573	MDM-513_H5N1_MOI0_12h	MDM-513_H5N1_MOI2_12h	down	-1.69	6.88e-06	RNA-Seq data

Human tissue specific expression (TPM)

Expression value is measured by Transcripts Per Million (TPM)

Ensembl ID:	ENSG00000109787
Gene description:	Kruppel like factor 3
Chromosome:	4
Position	38664196-38701042
Protein class:	Predicted intracellular proteins, Transcription factors
Evidence:	Evidence at protein level
Subcellular location:	Nucleoplasm