P55209 (NAP1L1)

Homo sapiens

P27958 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
Networks viewer (Cytoscape.js) and color tagging feature require Firefox or Chrome browsers to work properly

Human protein: NP1L1_HUMAN

UniProtID: P55209

Gene name(s): NAP1L1;NRP

Protein name: Nucleosome assembly protein 1-like 1

Gene ID: 4673

HDF/HRF: NA

Virus protein: POLG_HCVH (HCV-H)

UniProtID: P27958

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P55209-P27958PHISTO,biogrid,HPIDB,VirusMentha18985028,22810585two hybrid,tandem affinity purification

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.978). Show
DDI evidence: yes (score 0.045). Show
Machine learning evidence: yes (score 0.327).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
3055Nop56p-associated pre-rRNA complex1040.12 (12/104)12777385CORUMView
2146Ribosome, cytoplasmic1430.13 (18/143)NAhu.MAPView
2692Nop56p-associated pre-rRNA complex50.40 (2/5)NAhu.MAPView
2985Ribosome, cytoplasmic1390.12 (16/139)NAhu.MAPView
3261NAP1L4-HIST1H1T-UTP15-NAP1L140.50 (2/4)NAhu.MAPView
3692Nop56p-associated pre-rRNA complex60.33 (2/6)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_DeltaE_15hpidown-2.453.08e-07Microarray data
GSE30589Vero_E6_Mock_infected_15hpiVero_E6_SARS-Cov_WT_15hpidown-2.548.32e-07Microarray data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-1.771.31e-05Microarray data
GSE32155CRL-5800_unifectedCRL-5807_infecteddown-3.081.00e-05Microarray data
GSE32155CRL-5810_unifectedCRL-5807_infecteddown-1.671.80e-04Microarray data
GSE65574MCL001_mock_24hMCL001_d3-5-MERS_24hdown-2.218.82e-04Microarray data

Human tissue specific expression (TPM)

Small intestine: 105.9 Liver: 58.2 Gallbladder: 344.4 Duodenum: 77.3 Rectum: 137.2 Tonsil: 353.9 Stomach: 108.7 Salivary glanda: 84.2 Adipose tissue: 234.0 Lung: 249.6 Lymph node: 524.0 Pancreas: 28.9 Kidney: 141.5 Colon: 119.2 Appendix: 287.6 Smooth musle: 282.3 Breast: 295.5 Parathyroid gland: 206.1 Esophagus: 167.4 Heart muscle: 164.3 Spleen: 384.4 Skeletal muscle: 63.0 Bone marrow: 211.9 Skin: 169.8 Urinary bladder: 263.0 Cervix, uterine: 362.7 Endometrium: 433.3 Ovary: 742.4 Fallopian tube: 291.7 Seminal vesicle: 292.8 Prostate: 303.5 Epididymis: 210.2 Testis: 238.2 Placenta: 288.0 Thyroid gland: 297.2 Cerebral cortex: 310.2 Adrenal gland: 383.2
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000187109
Gene description:Nucleosome assembly protein 1 like 1
Chromosome:12
Position76036587-76085033
Protein class:Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Microtubules