P51959 (CCNG1)

Homo sapiens

P27958-PRO_0000037566 (NA)

Hepatitis C virus genotype 1a (isolate H) (HCV)
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Human protein: CCNG1_HUMAN

UniProtID: P51959

Gene name(s): CCNG1;CCNG;CYCG1

Protein name: Cyclin-G1

Gene ID: 900

HDF/HRF: NA

Virus protein: Core protein p21(POLG_HCVH) (HCV-H)

UniProtID: P27958-PRO_0000037566

Gene name(s): NA

Protein name: Genome polyprotein

Gene ID: NA

Viral family: Flaviviridae


InteractionSource databasePubMed IDDetection method
P51959-P27958-PRO_0000037566HPIDB23487458protein array

Evidence suggesting a protein interaction:

Interolog evidence: yes (score 0.696). Show
DDI evidence: none/insignificant.
Machine learning evidence: yes (score 0.678).
Combined Score: 1.000


Virally targeted human complex

Complex idComplex nameComplex sizeTarget ratioPudMed IDSourceDetail
2971CPSF4L-CCNG120.50 (1/2)NAhu.MAPView

Differentially expression condition

SeriesControlTreatmentRegulationLog2FCAdj.P.ValData type
GSE28166mock_infected_24hVN1203_infected_24hdown-2.372.70e-04Microarray data
GSE30723AMs_control_24hAMs_PR8_24hdown-1.542.41e-03Microarray data
GSE32140-GPL6480mock_for_RSV_2hRSV_infectiondown-2.412.54e-06Microarray data
GSE49628Bcells_QuiescentBcells_Activationup1.731.28e-03Microarray data
GSE59226ControlVirus_infectiondown-2.341.14e-04Microarray data
GSE65574MCL001_mock_12hMCL001_d3-5-MERS_12hup1.644.00e-03Microarray data
GSE99298mock_infected_0hhRSV_NS1_Y125A_infected_96hup3.141.21e-04RNA-Seq data

Human tissue specific expression (TPM)

Small intestine: 117.8 Liver: 65.2 Gallbladder: 87.6 Duodenum: 137.7 Rectum: 94.4 Tonsil: 42.5 Stomach: 53.3 Salivary glanda: 23.6 Adipose tissue: 54.8 Lung: 49.6 Lymph node: 54.9 Pancreas: 13.9 Kidney: 126.3 Colon: 66.7 Appendix: 39.9 Smooth musle: 76.0 Breast: 82.2 Parathyroid gland: 68.1 Esophagus: 53.0 Heart muscle: 33.2 Spleen: 48.9 Skeletal muscle: 56.8 Bone marrow: 23.6 Skin: 27.8 Urinary bladder: 80.0 Cervix, uterine: 94.3 Endometrium: 83.3 Ovary: 136.8 Fallopian tube: 100.0 Seminal vesicle: 77.4 Prostate: 113.9 Epididymis: 89.4 Testis: 39.1 Placenta: 76.2 Thyroid gland: 103.3 Cerebral cortex: 27.2 Adrenal gland: 63.5
Expression value is measured by Transcripts Per Million (TPM)
Low tissue specificity
Ensembl ID:ENSG00000113328
Gene description:Cyclin G1
Chromosome:5
Position163437569-163446151
Protein class:Cancer-related genes, Plasma proteins, Predicted intracellular proteins
Evidence:Evidence at protein level
Subcellular location:Nucleoplasm