Human protein: AMPH_HUMAN
UniProtID: P49418
Gene name(s): AMPH;AMPH1
Protein name: Amphiphysin
Gene ID: 273
HDF/HRF: NA
Virus protein: POLG_HCVH (HCV-H)
UniProtID: P27958
Gene name(s): NA
Protein name: Genome polyprotein
Gene ID: NA
Viral family: Flaviviridae
| Interaction | Source database | PubMed ID | Detection method |
|---|---|---|---|
| P49418-P27958 | biogrid,HPIDB | 16139795 | affinity chromatography technology |
| Interolog evidence: | none/insignificant. | |
| DDI evidence: | yes (score 0.008). | Show |
| Machine learning evidence: | yes (score 0.042). |
Virally targeted human complex
| Complex id | Complex name | Complex size | Target ratio | PudMed ID | Source | Detail |
|---|---|---|---|---|---|---|
| 2868 | SNARE complex (VAMP2, SNAP25, STX1a, CPLX2) | 60 | 0.05 (3/60) | NA | hu.MAP | View |
| 4195 | SNARE complex (VAMP2, SNAP25, STX1a, CPLX2) | 20 | 0.10 (2/20) | NA | hu.MAP | View |
Differentially expression condition
| Series | Control | Treatment | Regulation | Log2FC | Adj.P.Val | Data type |
|---|---|---|---|---|---|---|
| GSE97672-GPL16791 | MDM-315_H1N1_MOI0_18h | MDM-315_H1N1_MOI2_18h | up | 6.52 | 2.77e-02 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-513_H5N1_MOI0_06h | MDM-513_H5N1_MOI2_06h | up | 6.73 | 1.58e-02 | RNA-Seq data |
| GSE97672-GPL16791 | MDM-520_H5N1_MOI0_12h | MDM-520_H5N1_MOI2_12h | up | 2.89 | 4.95e-02 | RNA-Seq data |
| GSE97672-GPL18573 | MDM-513_H5N1_MOI0_12h | MDM-513_H5N1_MOI2_12h | up | 7.84 | 3.53e-04 | RNA-Seq data |
Human tissue specific expression (TPM)
Expression value is measured by Transcripts Per Million (TPM)
Tissue enriched:
| Tissue | Expression (TPM) |
|---|---|
| cerebral cortex | 83.7 |
| Ensembl ID: | ENSG00000078053 |
| Gene description: | Amphiphysin |
| Chromosome: | 7 |
| Position | 38383704-38631567 |
| Protein class: | Cancer-related genes, Predicted intracellular proteins |
| Evidence: | Evidence at protein level |
| Subcellular location: | Plasma membrane, Cytosol |